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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第106巻第6号

実験脳腫瘍の増殖能及び局所循環・代謝におよぼす放射線照射の影響

http://hdl.handle.net/10191/39777
http://hdl.handle.net/10191/39777
5ad84ea1-05fa-4525-959c-6f7fe3ac79a3
名前 / ファイル ライセンス アクション
106(06)_528-535.pdf 106(06)_528-535.pdf (1.4 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2016-03-15
タイトル
タイトル 実験脳腫瘍の増殖能及び局所循環・代謝におよぼす放射線照射の影響
タイトル
言語 en
タイトル 実験脳腫瘍の増殖能及び局所循環・代謝におよぼす放射線照射の影響
言語
言語 jpn
キーワード
主題Scheme Other
主題 cell proliferation
キーワード
主題Scheme Other
主題 CBF and metabolism
キーワード
主題Scheme Other
主題 irradiation
キーワード
主題Scheme Other
主題 rat brain tumor
キーワード
主題Scheme Other
主題 細胞増殖能
キーワード
主題Scheme Other
主題 循環代謝
キーワード
主題Scheme Other
主題 放射線照射
キーワード
主題Scheme Other
主題 実験脳腫瘍
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル Changes of DNA Synthesis, Blood Flow and Metabolism in Experimental Brain Tumors after Irradiation
著者 伏島, 徹

× 伏島, 徹

WEKO 128559

伏島, 徹

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著者別名
識別子 128560
識別子Scheme WEKO
姓名 Fusejima, Toru
抄録
内容記述タイプ Abstract
内容記述 The growth rate, local cerebral blood flow (LCBF), local cerebral glucose utilization (LCGU), local cerebral protein synthesis (LCPS) or DNA synthesis of brain tumors were studied in experimental rat brain tumors before and after irradiation, using quantitative autoradiography and immunohistochemical techniques. Two strains of rat brain tumor induced by Rous sarcoma virus were used. Strain A was biologically more malignant and less sensitive to radiation than strain B. The LCGU, LCPS and DNA synthesis reduced after irradiation but the LCBF changed little in both A and B tumors. The value of LCGU in the tumor decreased slowly after irradiation. The reduction rate was greater in strain B tumor than in strain A tumor. The value of LCPS decreased rapidly after irradiation in both tumors. The reduction rate was greater in strain B tumor than in strain A tumor. The labeling index of S-phase cells (LI) decreased rapidly, as much as that of LCPS, after irradiation in both tumors and the reduction rate of LI was also greater in strain B tumor than in strain A tumor. These findings indicate that the reduction of LCPS, DNA synthesis and LCGU may represent the radiosensitivity of these tumors. The reduction of LCPS and LI occured earlier than those of LCGU and tumor size. The radiosensitivity of tumors could be predicted by measuring the changes in LI and LCPS before recognition of the reduction in tumor size.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 106, 号 6, p. 528-535, 発行日 1992-06
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
値 publisher
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