{"created":"2021-03-01T06:25:56.058666+00:00","id":20933,"links":{},"metadata":{"_buckets":{"deposit":"d372ae13-5e2d-4511-aa54-22ef6dc44ff2"},"_deposit":{"id":"20933","owners":[],"pid":{"revision_id":0,"type":"depid","value":"20933"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00020933","sets":["453:456","471:537:538:1173"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Effects of Taraxacum-Extract on the Isolated Rat Aorta"}]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1992-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"517","bibliographicPageStart":"513","bibliographicVolumeNumber":"106","bibliographic_titles":[{"bibliographic_title":"新潟医学会雑誌"},{"bibliographic_title":"新潟医学会雑誌","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Using the isolated rat aortas with or without endothelium, the effects of Taraxacum-extract on the vascular smooth muscle were studied. The contraction was induced by phenylephreine. In the preparations without endothelium Taraxacum-extract produced a dose-dependent increase in tension, while in preparations with intact endothelium high doses (0.1 and 0.3ml) of this extract produced relaxation. Taraxacum contained 265mM K^+ and 53mM Na^+. However, the solution containing 265mM K^+ and 53mM Na^+ induced only a contraction at a higher dose (0.03ml). The contraction was greater in the aorta without entodthlium than in the aorta with endothelium. Indomethacin(10^<-5> .M) had no effect on the Taraxacum-extract-induced relaxation, while the contraction induced with lower concentrations of Taraxacum-extract was potentiated. These results indicate that Taraxacum-extract produces endothelium-dependent relaxation (due probably to EDRF) at higher doses. The release of vasorelaxant prostaglandin(s) was indicated. The contraction induced with Taraxacum-extract was not due to K^+ and Na^+ ion contained in it.","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"128555","nameIdentifierScheme":"WEKO"}],"names":[{"name":"You, Chun-lai"}]},{"nameIdentifiers":[{"nameIdentifier":"128556","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Nakazawa, Mikio"}]}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟医学会"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00182415","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00290440","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"尤, 春来"}],"nameIdentifiers":[{"nameIdentifier":"128553","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"仲澤, 幹雄"}],"nameIdentifiers":[{"nameIdentifier":"128554","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-16"}],"displaytype":"detail","filename":"106(06)_513-517.pdf","filesize":[{"value":"900.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"106(06)_513-517.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/20933/files/106(06)_513-517.pdf"},"version_id":"a5b6453c-83df-4646-9c1f-4fcdc86552c6"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Taraxacum","subitem_subject_scheme":"Other"},{"subitem_subject":"rat aorta","subitem_subject_scheme":"Other"},{"subitem_subject":"vascular smooth muscle","subitem_subject_scheme":"Other"},{"subitem_subject":"蒲公英","subitem_subject_scheme":"Other"},{"subitem_subject":"ラット大動脈","subitem_subject_scheme":"Other"},{"subitem_subject":"血管平滑筋","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"ラット摘出大動脈平滑筋に対する蒲公英の作用","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ラット摘出大動脈平滑筋に対する蒲公英の作用"},{"subitem_title":"ラット摘出大動脈平滑筋に対する蒲公英の作用","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","1173"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-03-15"},"publish_date":"2016-03-15","publish_status":"0","recid":"20933","relation_version_is_last":true,"title":["ラット摘出大動脈平滑筋に対する蒲公英の作用"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:51:34.338168+00:00"}