@article{oai:niigata-u.repo.nii.ac.jp:00020815, author = {和田, 研}, issue = {8}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Aug}, note = {Thrombosis is one of the main complications in patients with renal diseases, especially nephrotic syndrome. Previously, urinary FDP or fibrinopeptide A has been used as a thrombotic markers in these patients. I measured plasma levels of various coagulation and fibrinolytic markers in 32 patients with renal diseases. Plasma concentration of plasmin-α_2-plasmin inhibitor complex (PIC), thrombin-antithrombin III complex (TAT) and D-dimer were significantly elevated in patients with renal diseases as compared to healty subjects;0.85±0.70 vs 0.24±0.13 μg/ml, 2.94±1.11 vs 1.86±0.47 μg/1,185.58±269.41 vs 30±14 ng/ml, respectevely. Plasma PIC and TAT levels were relatively high in patients with rapidly progressive glomerular nephntis (RPGN) and lupus glomerular nephritis (lupus GN). These findings indicate that these molecular markers were useful for the assessment of hypercoagulable and/or hyperfibrinolytic renal diseases.}, pages = {739--743}, title = {各種腎疾患における血液凝固線溶分子マーカーの検討}, volume = {106}, year = {1992} }