@article{oai:niigata-u.repo.nii.ac.jp:00020754, author = {柳澤, 善計}, issue = {9}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Sep}, note = {In order to investigate the energy metabolism of the gastric wall, ^<31>P-magnetic resonance spectroscopy (^<31>P-MRS) with surface coil was performed in the rat stomach under the following conditions. By reducing the systemic blood pressure to 50% below (hemorrhage from the artery), the blood flow of the gastric wall decreased less than 50%, and recovered to normal range after retransfusion. In such ischemic condition, phospocreatine (PCr)/inorganic phosphate (Pi) ratio and β-ATP/Pi ratio of the gastric wall decreased, and their ratio recovered to previous values after retransfusion. Intracellular pH of gastric wall decreased during hypotension and recovered to previous after retransfusion. After administration of the endothelin in the artery, the blood flow of the gastric wall also decreased to 50~60% of that before administration. Also this condition induced PCr/Pi ratio and β-ATP/Pi ratio decreased. In summary, experimental ulcer stomach showed negative response of high-energy phosphate compounds when it was assessed by ^<31>P-MRS.}, pages = {867--874}, title = {^<31>P-MRSによる胃潰瘍モデルラット胃壁の高エネルギー燐化合物の動態に関する検討}, volume = {106}, year = {1992} }