@article{oai:niigata-u.repo.nii.ac.jp:00020749, author = {石田, 道雄}, issue = {9}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Sep}, note = {In order to establish the appropriate way of the counselling for couples with chromosomal aberration and recurrent or habitual abortion, the more substantial method for the prediction of pregnant prognosis in these patients was sought from the results of genetic counselling performed at genetic counselling outpatient clinic, department of obstetrics and gynecology, Niigata University School of Medicine, between April, 1982 and April, 1991. The results were as follows: 1) Out of 104 couples with recurrent abortion who were offered genetic counselling during indicated period at our outpatient clinic, in 29, the chromosomal aberration was observed. 2) Of twenty-nine couples, in 15, the wives were carriers, and in remaining 14, the husbands were carriers. 3) The chromosomal aberrations included 12 cases of reciprocal translocation, 6 cases of Robertsonian translocation, 4 cases of pericentric inversion, 4 cases of sex chromosome aneuploidy, 1 case of 14 p^+, 1 case of 22 p^+ and 1 case of Yq^+. 4) Relatively high rates of spontaneous abortion were obatained by accumulation of past pregnant history in patients with chromosomal aberration compared with the theoretical risks of abortion. 5) Application of empiric risks was considered to be more approapriate and practical for predicting the prognosis of further pregnancy for the couples of recurrent or habitual abortion with chromosomal aberration.}, pages = {824--835}, title = {反復・習慣流産の原因としての染色体異常保因者への遺伝外来における対応に関する検討}, volume = {106}, year = {1992} }