@article{oai:niigata-u.repo.nii.ac.jp:00020568, author = {田村, 哲郎}, issue = {11}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Nov}, note = {In order to investigate the pseudocapsule, histological and immunohistochemical studies were performed on adenomas and pseudocapsules or periadenomatous pituitary glands obtained from 61 pituitary operations (acromegaly 34, prolactinoma 19, Cushing's disease 8). The pseudocapsule was observed in 41 cases (67.2%). The incidence was higher in acromegaly (26/34, 76.5%) than prolactinoma (13/19, 68.4%) and Cushing's disease (2/8, 25.0%). Histologically, the pseudocapsule was the tissue composed of the compressed alveolar structure with fibrosis. Immunohistochemistry demonstrated that many kinds of anterior pituitary hormone positive cells were scattered in the pseudocapsule. Some pseudocapsule (9/41, 22.0%) partly contained adenoma cells. From these observations, it is concluded that the pseudocapsule is mainly composed of normal pituitary gland compressed by the tumor. Pseudocapsulectomy after selective adenomectomy is recommended to achieve endocrinological cure in the treatment of the functioning pituitary adenomas.}, pages = {1036--1040}, title = {機能性下垂体腺腫の境界部組織(pseudocapsule)の免疫組織化学的研究}, volume = {106}, year = {1992} }