@article{oai:niigata-u.repo.nii.ac.jp:00020337, author = {黒崎, 功}, issue = {2}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Feb}, note = {Pathological investigation on 83 surgical specimens from patients with carcinoma of the extrahepatic bile duct was carried out to evaluate the mode of growth, the degree of infiltration, and the location of the tumor, from the view-point of obstructive mechanism of the duct lumen. 7 of the 12 early carcinomas were located in the intrapancreatic bile duct and 8 were pedunculated or broadbased type in gross shape, protruding into the duct lumen. And tumors of pedunculated type were suggested to infiltrate to the subserosal layer kept in same gross shape. The advanced carcinoma cases with major axis of subserosal lesion less than 10mm showed better prognosis than the cases with that greater than 10mm, but frequency of lymphnodal metastases was not significantly different between two groups of cases. The major axis of subserosal lesion in the intrapancreatic advanced carcinoma was shorter than that in extrapancreatic. It was suggested that the intrapancreatic carcinoma had been detected in more early phase of carcinoma spreading. Therefore, the reason that the prognosis of the intrapancreatic carcinoma was better than that of the extrapancreatic was considered to be the different the mode of spreading according to the tumor location.}, pages = {124--132}, title = {胆管内腔の狭小化機転からみた肝外胆管癌の病理学的特徴}, volume = {107}, year = {1993} }