@article{oai:niigata-u.repo.nii.ac.jp:00020268,
 author = {金子, 一郎},
 issue = {3},
 journal = {新潟医学会雑誌, 新潟医学会雑誌},
 month = {Mar},
 note = {Even though prognosis of Idiopathic Portal Hypertension (IPH) is thought to be relatively favorable, death in the 5th or 6th decade of age is often encountered. In this study, long results of non-shunting surgery for 50 patients with IPH was evaluated in order to identify the prognostic factors. Cumulative 10 year survival rate after non-shunting surgery for esophageal varices was 73% and late death after 10 years was frequently encountered in addition. Main causes of late death were hepatic failure in the earlier postoperative phase (within 5 years) and infection in the later phase (after 10 years). Risk of hepatic failure was high in patients who showed prominent inflammatory cell infiltration in the portal tract of the liver and slightly elevated serum transaminase level. Male sex and habitual alcohol intake were also seemed to be unfavorable factors. Although various immunologic abnormalities are evident in IPH patients, it was not clear whether the fatal infection occurred in 5 patients at the age of 58 in average actually related to IPH itself. All 5 patients but one with diabetes mellitus had undergone splenectomy. Postsplenectomy state of immunologic defense system in IPH patients must be investigated urgently.},
 pages = {247--256},
 title = {特発性門脈圧亢進症の長期予後食道静脈瘤に対する外科治療症例の検討},
 volume = {107},
 year = {1993}
}