@article{oai:niigata-u.repo.nii.ac.jp:00020264,
 author = {吉澤, 豊久 and 阿部, 春樹 and 岩田, 和雄 and 安藤, 誠男 and 板東, 武彦},
 issue = {3},
 journal = {新潟医学会雑誌, 新潟医学会雑誌},
 month = {Mar},
 note = {The intraocular pressure is maintained within the narrow normal range in human, to keep the eye balls constant shape. The regulation of IOP consists of the neural, mechanical, and humoral controls. The sympathetic and parasympathetic inputs to regulate IOP are known, and also the sensory output from the eye to detect the IOP level has been reported. Since 1950's it was been suggested that the central nervous system (CNS), especially the hypothalamus plays an important role in regulating IOP. We investigated the effect of microiontophoretic application of vasopressin (VP) and oxytocin (OXT) into the cat hypothalamus on IOP. The goal was to understand better the mechanisms of IOP regulation by the CNS. Under sodium pentobarbital anesthesia (35 mg/kg, i. p. ), the cats were fixed in a stereotaxic apparatus. The IOP and blood pressure (BP) were recorded continuously. A three-barreled glass micropipette was used; VP, OXT, and saline were applied iontophoretically into the hypothalamus. When VP or OXT was injected in and around the supraoptic nucleus and the paraventricular nucleus, the IOP was elevated gradually. When saline was applied to the same point, the IOP showed no change. It is concluded that this experimental model is very useful to study the regulatory mechanism of IOP in the CNS.},
 pages = {220--223},
 title = {3）眼圧と中枢神経系の関連について(シンポジウム 視覚の生理学, 第478回新潟医学会)},
 volume = {107},
 year = {1993}
}