@article{oai:niigata-u.repo.nii.ac.jp:00020262,
 author = {阿部, 春樹 and 長谷川, 茂 and 高木, 峰夫 and 吉澤, 豊久 and 臼井, 知聡},
 issue = {3},
 journal = {新潟医学会雑誌, 新潟医学会雑誌},
 month = {Mar},
 note = {Subjective temporal modulation transfer function (temporal MTF) were measured in 21 eyes of 14 patients with optic neuritis (age range 24 to 62 years) to clarify the temporal characteristics of central visual function. Servings as controls were 88 eyes of 46 normal subjects (age range 25 to 69 years) who were devided into two groups, those younger than and those older than 45 years of age, whereby normal values were obtained. After age matching, patient's values were compared with those of normal subjects. In normal subjects, the subjective temporal modulation sensitivity showed the maxinum peak at the temporal frequency of 10 to 15 Hz, and the significant deterioration of temporal modulation sensitivity by aging was found at the temporal frequency from 15 to 50 Hz. With regard to the 21 eyes of 14 patients with optic neuritis, attenuation of temporal modulation sensitivity at all temporal frequencies was seen in the acute phase, and the recovery of temporal modulation sensitivity occurred at first at lower temporal frequency and then from middle to high temporal frequencies. To estimate temporal MTF and temporal characteristics of central visual function objectively, the pattern VEPs were recorded in 14 eyes of patients with optic neuritis and 15 eyes of normal controls using checkerboard pattern (check size 14.4') which was reversed at the frequency ranging from 4 to 16 per second. Fast Fourier Transform (FFT) of the pattern VEPs was investigated and analyzed to clarify the difference of temporal frequency charecteristics between normal subjects and patients with optic neuritis. In normal subjects the curves of square root of the power of FFT of P-VEP vs temporal frequency showed the maxinum peak at 6 Hz (12 reversal per second). Specific distribution of power spectrum could be found at each temporal frequencies, and the amplitudes of higher harmonic components decreased and a single peak of power spectrum became prominent as the temporal frequency increased. In patients with optic neuritis, the abnormality of power spectrum of steady-state P-VEPs could be detected by estimating 1st or 2nd harmonic components. The abnormality of power spectrum of transient P-VEPs could be detected by estimating higher harmonic components of power spectrum.},
 pages = {208--215},
 title = {1）視覚の空間・時間周波数特性 第2報 視覚の時間周波数特性の検討(シンポジウム 視覚の生理学, 第478回新潟医学会)},
 volume = {107},
 year = {1993}
}