@article{oai:niigata-u.repo.nii.ac.jp:00020261, author = {阿部, 春樹 and 長谷川, 茂 and 高木, 峰夫 and 吉澤, 豊久 and 臼井, 知聡}, issue = {3}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Mar}, note = {Subjective and objective spatial contrast sensitivity (spatial modulation transfer function) were measured in ten eyes of five patients with ocular hypertension (age range 18 to 51 years) and 94 eyes of 55 patients with primary open-angle glaucoma (POAG; age range 16 to 74 years). Servings as controls were 83 eyes of 47 normal subjects (age range 15 to 72 years) who were devided into two groups, those younger than and those older than 40 years of age, whereby normal values were obtained. After age matching, patient's values were compared with those of normal subjects. In normal subjects, the subjective spatial contrast sensitivity showed the maximum peak at the spatial frequency of 3.12 cycle/degree, and the significant deterioration of contrast sensitivity by aging was found at all spatial frequencies (0.78~12.4 cycle/degree) examined. With regard to the 94 eyes of 55 patients with POAG, the deterioration of spatial contrast sensitivity became prominent and frequent as the optic nerve damage progressed, and those with high spatial frequency loss comprised the largest group of 40%, followed by the low spatial frequency loss of 21%, level loss of 21% and normal group represented 18% of the study population. To estimate spatial MTF objectively, the peak latency of P_<100> component of pattern VEP was investigated. VEP data were obtained using checkerboard pattern stmuli counterphase-alternated at 1.25 Hz. Four check sizes (3.6, 7.2, 14.4 and 28.8 min. of arc) and four contrast levels (2, 5, 10 and 50%) were used. The mean contrast sensitivity in normal subjects, derived from VEP peak latency, was found to be maximum at 14.4 min. of arc, and the objective spatial MTF curve coincided well with that of the subjective one at all spatial frequencies examined. The statistically significant positive correlation was found between objective contrast threshold and subjective one (the coefficient of correlation was 0.725 (p<0.005)). The deterioration of objective spatial contrast sensitivity, derived from VEP peak latency, was found to be much more prominent than that of the subjective one in patients with glaucoma.}, pages = {201--208}, title = {1)視覚の空間・時間周波数特性 第1報 視覚の空間周波数特性の検討(シンポジウム 視覚の生理学, 第478回新潟医学会)}, volume = {107}, year = {1993} }