{"created":"2021-03-01T06:25:05.506847+00:00","id":20166,"links":{},"metadata":{"_buckets":{"deposit":"5904919c-a8f4-4845-a13f-70421b40ce7d"},"_deposit":{"id":"20166","owners":[],"pid":{"revision_id":0,"type":"depid","value":"20166"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00020166","sets":["453:456","471:537:538:1162"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"A Combination Chemotherapy Consisting of Adriamycin, Vincristine, Etoposide and Cyclophosphamide (AVEC therapy) for Small Cell Lung Cancer"}]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1993-05","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"450","bibliographicPageStart":"444","bibliographicVolumeNumber":"107","bibliographic_titles":[{"bibliographic_title":"新潟医学会雑誌"},{"bibliographic_title":"新潟医学会雑誌","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Twenty patients with small cell lung cancer (SCLC), 11 limited disease (LD) and 9 had extensive disease (ED), were treated with a combination chemotherapy consisting of ADM (40mg/m^2, i.v., day 1), VCR (1mg/m^2, i.v., day 1), ETP (60mg/m^2, i.v., day 1～5) and CPA (600mg/m^2, i.v., day 1) (AVEC therapy) at 4week intervals. The overall response rate and the complete response (CR) rate were 100% (11/11) and 36% (4/11) in LD cases, and 78% (7/9) and 0% (0/9) in ED cases, respectively. The median response duration were 9 months in LD cases and 2 months in ED cases. The median survival time of LD, ED and all cases were 13, 9 and 13 months, respectively. The over 3 years survival rate was 20% (4/20). The major toxicity was myelosupression, although it was well tolerated. These results suggest that the AVEC therapy is effective for SCLC.","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"124714","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Nakajima, Yoshiaki"}]},{"nameIdentifiers":[{"nameIdentifier":"124715","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Hatakeyama, Shinobu"}]},{"nameIdentifiers":[{"nameIdentifier":"124716","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Suzuki, Eiichi"}]},{"nameIdentifiers":[{"nameIdentifier":"124717","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Nagai, Akihiko"}]},{"nameIdentifiers":[{"nameIdentifier":"124718","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Kioi, Satoru"}]},{"nameIdentifiers":[{"nameIdentifier":"124719","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Arakawa, Masaaki"}]},{"nameIdentifiers":[{"nameIdentifier":"124720","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Tawaraya, Kouzou"}]},{"nameIdentifiers":[{"nameIdentifier":"124721","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Haraguchi, Michihiko"}]}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟医学会"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00182415","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00290440","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"中島, 喜章"}],"nameIdentifiers":[{"nameIdentifier":"124706","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"畠山, 忍"}],"nameIdentifiers":[{"nameIdentifier":"124707","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鈴木, 栄一"}],"nameIdentifiers":[{"nameIdentifier":"124708","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"永井, 明彦"}],"nameIdentifiers":[{"nameIdentifier":"124709","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"来生, 哲"}],"nameIdentifiers":[{"nameIdentifier":"124710","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"荒川, 正昭"}],"nameIdentifiers":[{"nameIdentifier":"124711","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"俵谷, 幸蔵"}],"nameIdentifiers":[{"nameIdentifier":"124712","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"原口, 通比古"}],"nameIdentifiers":[{"nameIdentifier":"124713","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-16"}],"displaytype":"detail","filename":"107(5)_444-450.pdf","filesize":[{"value":"1.4 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"107(5)_444-450.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/20166/files/107(5)_444-450.pdf"},"version_id":"950df9a2-bd19-4bf8-97d9-6a3262a0d526"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Small Cell Lung Cancer","subitem_subject_scheme":"Other"},{"subitem_subject":"Combination Chemotherapy","subitem_subject_scheme":"Other"},{"subitem_subject":"Adriamycin","subitem_subject_scheme":"Other"},{"subitem_subject":"Vincristine","subitem_subject_scheme":"Other"},{"subitem_subject":"Etoposide","subitem_subject_scheme":"Other"},{"subitem_subject":"Cyclophosphamide","subitem_subject_scheme":"Other"},{"subitem_subject":"肺小細胞癌","subitem_subject_scheme":"Other"},{"subitem_subject":"多剤併用科学療法","subitem_subject_scheme":"Other"},{"subitem_subject":"アドリアマイシン","subitem_subject_scheme":"Other"},{"subitem_subject":"ビンクリスチン","subitem_subject_scheme":"Other"},{"subitem_subject":"エトポシド","subitem_subject_scheme":"Other"},{"subitem_subject":"サイクロフォスファマイド","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin 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