{"_buckets": {"deposit": "017143af-6aba-4934-a114-e105efbfd91e"}, "_deposit": {"id": "20121", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "20121"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00020121"}, "item_7_alternative_title_1": {"attribute_name": "\u305d\u306e\u4ed6\u306e\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_alternative_title": "Effects of Antiarrhythmic Agents on Low-perfusion Induced Arrhythmia in Isolated Rat Heart"}]}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1993-06", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "6", "bibliographicPageEnd": "522", "bibliographicPageStart": "512", "bibliographicVolumeNumber": "107", "bibliographic_titles": [{"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c"}, {"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "In the isolated perfused rat heart, low-flow perfusion (0.5ml/min) resulted in a marked reduction of the left ventricular developed pressure. Ventricular arrhythmia developed and the ventricular endsiastolic pressure rose 10 min after initiation of low-flow perfusion. In the vehicletreated hearts the total arrhythmic period during 20 min of low-flow perfusion was 436\u00b136 sec. The period was shorter in the presence of lidocaine, diltiazem and propranolol and the rise of EDP was attenuated. E-4031, a blocker of the delayed rectifier K channel, produced a shortening of the arrhythmic period and an attenuation of the rise of EDP only at a high concentration (100\u03bcM). In contrast, glibenclamide, a blocker of ATP-sensitive K channel, and bretylium, a quaternary ammonlum salt, reduced arrhthmic period without producing attenuation of the rise of EDP. These effects were inhibited by cromakalim, an ATP-sensitive K channel opener. Thus, the antiarrhythmic effects of diltiazem, propranolol, lidocaine and E-4031 were due to antiischemic action, while those of glibenclamide and bretylium were probably attributable to blockade of ATP-sensitive K channel.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "\u8457\u8005\u5225\u540d", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "124472", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Ohta, Hideo"}]}]}, "item_7_publisher_7": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "\u65b0\u6f5f\u533b\u5b66\u4f1a"}]}, "item_7_select_19": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "\u592a\u7530, \u82f1\u7537"}], "nameIdentifiers": [{"nameIdentifier": "124471", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-16"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "107(6)_512-522.pdf", "filesize": [{"value": "1.7 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1700000.0, "url": {"label": "107(6)_512-522.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/20121/files/107(6)_512-522.pdf"}, "version_id": "6a9ebffe-d6e7-4e5f-9f97-57eb7761aee4"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "Ischemia", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Arrhythmia", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Langendorff", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Antiarrhythmic agent", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u865a\u8840", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u4e0d\u6574\u8108", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u6458\u51fa\u5fc3\u81d3\u704c\u6d41\u6a19\u672c", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u6297\u4e0d\u6574\u8108\u85ac", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "\u30e9\u30c3\u30c8\u6458\u51fa\u5fc3\u306b\u304a\u3051\u308b\u4f4e\u704c\u6d41\u6642\u4e0d\u6574\u8108\u306b\u5bfe\u3059\u308b\u5404\u7a2e\u6297\u4e0d\u6574\u8108\u85ac\u306e\u52b9\u679c", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "\u30e9\u30c3\u30c8\u6458\u51fa\u5fc3\u306b\u304a\u3051\u308b\u4f4e\u704c\u6d41\u6642\u4e0d\u6574\u8108\u306b\u5bfe\u3059\u308b\u5404\u7a2e\u6297\u4e0d\u6574\u8108\u85ac\u306e\u52b9\u679c"}, {"subitem_title": "\u30e9\u30c3\u30c8\u6458\u51fa\u5fc3\u306b\u304a\u3051\u308b\u4f4e\u704c\u6d41\u6642\u4e0d\u6574\u8108\u306b\u5bfe\u3059\u308b\u5404\u7a2e\u6297\u4e0d\u6574\u8108\u85ac\u306e\u52b9\u679c", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["453/456", "471/537/538/1161"], "permalink_uri": "http://hdl.handle.net/10191/37452", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2016-02-03"}, "publish_date": "2016-02-03", "publish_status": "0", "recid": "20121", "relation": {}, "relation_version_is_last": true, "title": ["\u30e9\u30c3\u30c8\u6458\u51fa\u5fc3\u306b\u304a\u3051\u308b\u4f4e\u704c\u6d41\u6642\u4e0d\u6574\u8108\u306b\u5bfe\u3059\u308b\u5404\u7a2e\u6297\u4e0d\u6574\u8108\u85ac\u306e\u52b9\u679c"], "weko_shared_id": null}