@article{oai:niigata-u.repo.nii.ac.jp:00020118, author = {上野, 光博 and 荒川, 正昭}, issue = {6}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Jun}, note = {Intrarenal vascular lesions of diabetic glomerulosclerosis were evaluated in order to clarify the relationship between vascular lesions and diabetic nephropathy in 108 NIDDM patients. Index of arteriolar hyalinous change (IAHC), designed as grade of AHC, was correlated significantly with age at biopsy, DM duration, GFR, PSP (15'), urine protein, systolic blood pressure (BP) and index of glomerular lesion (IGL). IAHC was also higher in hypertensive patients than in normotensive patients. Intimal thickening of small arteries (IT/SA) had a significant correlation with DM duration, systolic BP, GFR and Fishberg's concentration test. IAHC and IGL were significantly higher in IT/SA (+) group than in IT/SA (-) group. Intimal thickening of arteries (IT/A) was not related with clinical findings, although IAHC was significantly higher in IT/A (+) group. In conclusion, arteriolar hyalinosis may be closely related to the progression of diabetic nephropathy and intimal thickening of small arteries and arteries may contribute as well.}, pages = {490--496}, title = {5) 糖尿病性腎症の血管障害(シンポジウム 血管障害の発生メカニズムと予防, 第473回新潟医学会)}, volume = {107}, year = {1993} }