{"created":"2021-03-01T06:24:56.844417+00:00","id":20033,"links":{},"metadata":{"_buckets":{"deposit":"ab8cc122-acbc-4e66-9682-2dd585ba461f"},"_deposit":{"id":"20033","owners":[],"pid":{"revision_id":0,"type":"depid","value":"20033"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00020033","sets":["453:456","471:537:538:1160"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"An Immunohistochemical Study of Anti-human-laminin Monoclonal Antibodies"}]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1993-07","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"7","bibliographicPageEnd":"601","bibliographicPageStart":"591","bibliographicVolumeNumber":"107","bibliographic_titles":[{"bibliographic_title":"新潟医学会雑誌"},{"bibliographic_title":"新潟医学会雑誌","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Immunohistochemical distribution of laminin was examined in human renal and placental tissue using anti-human-laminin monoclonal antibodies （1D8 and 6G5）, which recognized different parts of non-reduced laminin molecule. Both antibodies staind glomerular mesangial matrix and placental trophoblast basement membrane, however, glomerular basement membrane, Bowman's capsule, and tubular basement membrane were not stained. Fetal vessel wall in placenta had only limited reactivity with these two antibodies. Both tissue reduction and oxidation enhanced the reactivity of basement membrane to 1D8 but not that to 6G5. Expanded mesangial matrix in patients with diabetic nephropathy or IgA nephropathy were also stained with 1D8 and 6G5. These data suggest that laminin in extracellular matrix has immunological heterogeniety, which may be derived from masking of lammin epitopes by other matrix components or from heterogeniety of laminin chain itself.","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"124008","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Shimada, Hisaki"}]}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟医学会"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00182415","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00290440","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"島田, 久基"}],"nameIdentifiers":[{"nameIdentifier":"124007","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-16"}],"displaytype":"detail","filename":"107(7)_591-601.pdf","filesize":[{"value":"5.4 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"107(7)_591-601.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/20033/files/107(7)_591-601.pdf"},"version_id":"da474f01-9751-425b-beeb-a858684074da"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"laminin","subitem_subject_scheme":"Other"},{"subitem_subject":"immunohistchemistry","subitem_subject_scheme":"Other"},{"subitem_subject":"monoclonal antibody","subitem_subject_scheme":"Other"},{"subitem_subject":"diabetic nephropathy","subitem_subject_scheme":"Other"},{"subitem_subject":"IgA nephropathy","subitem_subject_scheme":"Other"},{"subitem_subject":"ラミニン","subitem_subject_scheme":"Other"},{"subitem_subject":"免疫組織化学","subitem_subject_scheme":"Other"},{"subitem_subject":"単クローン抗体","subitem_subject_scheme":"Other"},{"subitem_subject":"糖尿病性腎症","subitem_subject_scheme":"Other"},{"subitem_subject":"IgA 腎症","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"抗ラミニン単クローン抗体の染色性の検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"抗ラミニン単クローン抗体の染色性の検討"},{"subitem_title":"抗ラミニン単クローン抗体の染色性の検討","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","1160"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-02-04"},"publish_date":"2016-02-04","publish_status":"0","recid":"20033","relation_version_is_last":true,"title":["抗ラミニン単クローン抗体の染色性の検討"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:50:51.212484+00:00"}