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閉塞性睡眠時無呼吸症候群患者における鼻腔通気度計測による鼻腔抵抗と持続気道陽圧呼吸療法のアドヒアランスの関係
http://hdl.handle.net/10191/0002001869
http://hdl.handle.net/10191/0002001869ed378585-60c0-4442-9b08-8f60a795da85
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| アイテムタイプ | 学位論文 / Thesis or Dissertation(1) | |||||||||
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| 公開日 | 2025-06-24 | |||||||||
| タイトル | ||||||||||
| タイトル | The relationship between adherence to continuous positive airway pressure and nasal resistance measured by rhinomanometry in patients with obstructive sleep apnea syndrome | |||||||||
| 言語 | en | |||||||||
| タイトル | ||||||||||
| タイトル | 閉塞性睡眠時無呼吸症候群患者における鼻腔通気度計測による鼻腔抵抗と持続気道陽圧呼吸療法のアドヒアランスの関係 | |||||||||
| 言語 | ja | |||||||||
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| 言語 | eng | |||||||||
| 資源タイプ | ||||||||||
| 資源 | http://purl.org/coar/resource_type/c_db06 | |||||||||
| タイプ | doctoral thesis | |||||||||
| アクセス権 | ||||||||||
| アクセス権 | open access | |||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||
| 著者 |
藤戸, 信宏
× 藤戸, 信宏
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| 抄録 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | Nasal breathing disorders are associated with obstructive sleep apnea (OSA) syndrome and influence the availability of continuous positive airway pressure (CPAP) therapy. However, information is scarce about the impact of nasal resistance assessed by rhinomanometry on CPAP therapy. This study aimed to examine the relationship between CPAP adherence and nasal resistance evaluated by rhinomanometry, and to identify clinical findings that can affect adherence to CPAP therapy for patients with OSA. This study included 260 patients (199 men, 61 women; age 58 [interquartile ranges (IQR) 50–66] years) with a new diagnosis of OSA who underwent rhinomanometry (before, and 1 and 3 months after CPAP introduction) between January 2011 and December 2018. CPAP use was recorded, and the good and poor CPAP adherence groups at the time of patient registration were compared. Further-more, those with improved and unimproved pre-CPAP high rhinomanometry values were also compared. Their apnea-hypopnea index (AHI) by polysomnography at diagnosis was 45.6 (IQR 33.7–61.6)/hour, but the residual respiratory event (estimated AHI) at enrollment was 2.5 (IQR 1.4–3.9)/hour and the usage time was 318 (IQR 226–397) minutes, indicating that CPAP was effective and adherence was good. CPAP adherence was negatively corre-lated with nasal resistance (r = -0.188, p = 0.002). The participants were divided into good (n = 153) and poor (n = 107) CPAP adherence groups. In the poor adherence group, rhinoma-nometry values before CPAP introduction were worse (inspiration, p = 0.003; expiration, p = 0.006). There was no significant difference in patient background when comparing those with improved (n = 16) and unimproved (n = 12) pre-CPAP high rhinomanometry values. How-ever, CPAP usage time was significantly longer in the improved group 1 month (p = 0.002) and 3 months (p = 0.026) after CPAP introduction. The results suggest that nasal resistance evaluated by rhinomanometry is a useful predictor of CPAP adherence, and that improved rhinomanometry values may contribute to extending the duration of CPAP use. | |||||||||
| 言語 | en | |||||||||
| 内容記述 | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | Fujito N, Ohshima Y, Hokari S, Takahashi A, Nagai A, et al. (2023) The relationship between adherence to continuous positive airway pressure and nasal resistance measured by rhinomanometry in patients with obstructive sleep apnea syndrome. PLOS ONE 18(3): e0283070. https://doi.org/10.1371/journal.pone.0283070 | |||||||||
| 言語 | en | |||||||||
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| 識別子タイプ | DOI | |||||||||
| 関連識別子 | https://doi.org/10.1371/journal.pone.0283070 | |||||||||
| 権利 | ||||||||||
| 権利情報 | © 2023 Fujito et al. | |||||||||
| 言語 | en | |||||||||
| 権利 | ||||||||||
| 権利情報Resource | https://creativecommons.org/licenses/by/4.0/ | |||||||||
| 権利情報 | Creative Commons Attribution 4.0 International | |||||||||
| 言語 | en | |||||||||
| 学位名 | ||||||||||
| 学位名 | 博士（医学） | |||||||||
| 言語 | ja | |||||||||
| item_6_degree_grantor_49 | ||||||||||
| 学位授与機関識別子Scheme | kakenhi | |||||||||
| 学位授与機関識別子 | 13102 | |||||||||
| 学位授与機関名 | 新潟大学 | |||||||||
| 言語 | ja | |||||||||
| 学位授与機関名 | Niigata University | |||||||||
| 言語 | en | |||||||||
| 学位授与年月日 | ||||||||||
| 学位授与年月日 | 2024-09-20 | |||||||||
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| 学位授与番号 | 乙第2283号 | |||||||||
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| 内容記述タイプ | Other | |||||||||
| 内容記述 | 新大博（医）第1834号 | |||||||||
| 言語 | ja | |||||||||
