@phdthesis{oai:niigata-u.repo.nii.ac.jp:02000858,
 author = {Arabiki, Michiru and 荒引, みちる},
 month = {2023-03-07, 2023-03-07},
 note = {Purpose The 9th Japanese Classification of Colorectal Cancer (9th JSCCR) has two main differences from the TNM classification (8th AJCC): first, main or lateral lymph node metastasis is classified as jN3; second, tumor nodules (ND) are treated as lymph node metastasis. In this study, we verified the 9th JSCCR for rectal cancer, focusing on the differences with the 8th AJCC. Methods This retrospective analysis involved 212 patients with stage I-III rectal cancer. ND was evaluated using wholemount sections. We evaluated the relapse-free survival of each staging system, and compared the prognostic significance of the different staging systems using the Akaike information criterion (AIC) and Harrell's concordance index (c-index). Results Main or lateral lymph node metastasis was detected in nine of 212 (4%) patients. ND was detected in 79 of 212 (37%) patients. The best risk stratification power was observed in the 9th JSCCR (AIC, 759; c-index, 0.708) compared with the 7th JSCCR (AIC, 771; c-index, 0.681), 8th JSCCR (AIC, 768; c-index, 0.696), and the 8th AJCC (AIC, 766; c-index, 0.691). Conclusions The 9th JSCCR, which includes the concepts of jN3 and ND, is useful for the risk stratification of rectal cancer, and the contributes to precise decision-making for follow-up management and adjuvant therapy., Surgery today. 2020, 50(11), 1443-1451., 新大院博(医)第1072号},
 school = {新潟大学, Niigata University},
 title = {Verification of the Japanese staging system for rectal cancer, focusing on differences with the TNM classification},
 year = {}
}