{"created":"2022-10-20T06:31:12.647703+00:00","id":2000732,"links":{},"metadata":{"_buckets":{"deposit":"bb366f15-9a90-41f7-8dbe-0ab93b6b45ce"},"_deposit":{"id":"2000732","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"2000732"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:02000732","sets":["453:456","471:537:538:1666246832930"]},"author_link":[],"item_1627361970403":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-02","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"37","bibliographicPageStart":"33","bibliographicVolumeNumber":"136","bibliographic_titles":[{"bibliographic_title":"新潟医学会雑誌","bibliographic_titleLang":"ja"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"脳梗塞は重度の後遺症を呈する疾患であり，脳梗塞後の機能回復療法の開発が望まれている．近年，脳梗塞に対する細胞療法の研究が盛んに行われている．しかし，既存の細胞療法は，投与細胞の採取や調整に複雑な手技を要し，一般臨床への普及が難しい．我々は，炎症に作用すると考えられていたミクログリアや末梢血単核球に，低酸素低糖という簡便な刺激を加えることにより，脳梗塞に対して治療効果のある細胞を調整できることを証明した．本稿では，我々の開発した技術の背景と今後の展望について概説する．","subitem_description_language":"ja","subitem_description_type":"Abstract"}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟医学会","subitem_publisher_language":"ja"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00182415","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0029-0440","subitem_source_identifier_type":"PISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"金澤, 雅人","creatorNameLang":"ja"},{"creatorName":"Kanazawa, Masato","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2022-10-20"}],"displaytype":"detail","filename":"136(2)_33-37.pdf","filesize":[{"value":"954KB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://niigata-u.repo.nii.ac.jp/record/2000732/files/136(2)_33-37.pdf"},"version_id":"1372c3fc-3086-4b30-aed2-19081bb85b0f"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"脳虚血","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"再生医学","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"細胞療法","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"ミクログリア","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"末梢血単核球","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"低酸素低糖刺激","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"細胞修飾","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"低酸素低血糖刺激後のミクログリア・末梢血単核球による脳梗塞機能回復促進療法","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"低酸素低血糖刺激後のミクログリア・末梢血単核球による脳梗塞機能回復促進療法","subitem_title_language":"ja"},{"subitem_title":"Cell therapy using microglia or peripheral mononuclear cells preconditioned by oxygen - glucose deprivation against ischemic stroke","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","1666246832930"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-10-20"},"publish_date":"2022-10-20","publish_status":"0","recid":"2000732","relation_version_is_last":true,"title":["低酸素低血糖刺激後のミクログリア・末梢血単核球による脳梗塞機能回復促進療法"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-12-15T04:18:35.677133+00:00"}