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  1. 0 資料タイプ別
  2. 02 学位論文
  1. 250 大学院医歯学総合研究科(医)
  2. 60 博士学位論文
  3. 10 博士学位論文

外科治療を施行されたStanford A型急性大動脈解離患者における退院時心拍数と長期予後の関連について

http://hdl.handle.net/10191/0002000300
http://hdl.handle.net/10191/0002000300
97e83e20-6ef1-410e-bb05-1360efc8573a
名前 / ファイル ライセンス アクション
r2nmk995.pdf 本文 (1.11MB)
r2nmk995_a.pdf 要旨 (547KB)
Item type 学位論文 / Thesis or Dissertation(1)
公開日 2022-04-04
タイトル
言語 en
タイトル Relationship Between Heart Rate at Discharge and Long-Term Outcomes of Surgically Treated Patients With Type A Acute Aortic Dissections
タイトル
言語 ja
タイトル 外科治療を施行されたStanford A型急性大動脈解離患者における退院時心拍数と長期予後の関連について
言語
言語 eng
キーワード
言語 en
主題Scheme Other
主題 Aortic outcome
キーワード
言語 en
主題Scheme Other
主題 Discharge
キーワード
言語 en
主題Scheme Other
主題 Heart rate
キーワード
言語 en
主題Scheme Other
主題 Long term
キーワード
言語 en
主題Scheme Other
主題 Stanford type A acute aortic dissection
資源タイプ
資源 http://purl.org/coar/resource_type/c_db06
タイプ doctoral thesis
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
著者 萩谷, 健一

× 萩谷, 健一

en Hagiya, Kenichi

ja 萩谷, 健一

Search repository
抄録
内容記述タイプ Abstract
内容記述 Background: Resting heart rate (HR) at discharge is an important predictor of mortality after acute myocardial infarction. However, in patients with Stanford type A acute aortic dissections (TA-AADs), the relationship between HR and long-term outcomes is unclear. Therefore, this relationship was investigated in the present study. Methods and Results: Surgically treated consecutive patients with TA-AAD (n=721) were retrospectively categorized according to HR quartiles, recorded within 24h before discharge (<70, 70–77, 78–83, and ≥84beats/min). The study endpoints included aortic aneurysm-related deaths, sudden deaths, aortic surgeries, and hospitalizations for recurrence of acute aortic dissections. The mean (±SD) patient age was 65.8±13.0 years. During a median observation period of 5.8 years (interquartile range 3.9–8.5 years), 17.2% of patients (n=124) experienced late aortic events. Late aortic surgery was performed in 14.0% of patients. After adjusting for potential confounders, including β-blocker use, HR at discharge remained an independent predictor of long-term aortic outcomes. Patients with discharge HR ≥84beats/min had a higher risk (hazard ratio 1.86; 95% confidence interval 1.06–3.25; P=0.029) of long-term aortic events than those with HR <70beats/min; the cumulative survival rates were similar among the groups (log-rank, P=0.905). Conclusions: In surgically treated patients with TA-AAD, HR at discharge independently predicted long-term aortic outcomes. Consequently, HR in patients with TA-AAD should be optimized before discharge, particularly if the HR is ≥84beats/min.
言語 en
内容記述
内容記述タイプ Other
内容記述 Circulation Journal. 2021, 85(12), 2192-2200.
言語 en
DOI
識別子タイプ DOI
関連識別子 https://doi.org/10.1253/circj.CJ-20-0914
権利
言語 en
権利情報 All rights are reserved to the Japanese Circulation Society.
権利
言語 en
権利情報Resource https://creativecommons.org/licenses/by-nc-nd/4.0/
権利情報 Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
学位名
言語 ja
学位名 博士(医学)
学位授与機関
学位授与機関識別子Scheme kakenhi
学位授与機関識別子 13101
言語 ja
学位授与機関名 新潟大学
言語 en
学位授与機関名 Niigata University
学位授与年月日
学位授与年月日 2021-03-23
学位授与番号
学位授与番号 甲第4841号
学位記番号
内容記述タイプ Other
内容記述 新大院博(医)第995号
言語 ja
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