@article{oai:niigata-u.repo.nii.ac.jp:00019952,
 author = {田中, 久夫},
 issue = {8},
 journal = {新潟医学会雑誌, 新潟医学会雑誌},
 month = {Aug},
 note = {Infections with MRSA are encountered at a considerably high frequency in the field of otorhinolaryngology. The number of carriers, i.e., those who have no symptoms despite positive tests for MRSA, may outnumber actual patients by ten to one or even more. In Table 1, bacteria isolated from patients with typical otorhinolaryngological infections are shown together with the frequency of Staphylococcus aureus detection. S.aureus was detected frequently among these infections and was an important causative bacterium, particularly of chronic otitis media and chronic sinusitis. Table 3 shows annual changes in the detection rate for S.aureus and the proportion of MRSA in chronic otitis media. With the advent of third-generation cephem antibiotics in the first half of the 1980's, the detection rate for MRSA increased to more than 20%. In our hospital MRSA was first isolated in 1985 and has been found in about 15% of specimens in recent years. Among other otorhinolaryngological diseases, MRSA is detected more frequently in chronic diseases than in acute diseases. MRSA infection in patients with chronic otitis media and chronic sinusitis in the field of otorhinolaryngology is associated with characteristic features in that the lesion is highly resistant to nonsurgical methods of eradication, and that these diseases are refractory to conservative treament and the patient tends to have repeated infection. In addition to the high prevalence and pathogenicity of the bacterium, treatment involves repeated or long-term administration of antibiotics at a high frequency, thus leading to MRSA infection. Since the infection itself is not likely to be a lethal disease, the infected patient may become a carrier, providing a source of nosocomial infection. The infection may also cause pneumonia or bacteriemia if the patient's condition deteriorates for any reason.},
 pages = {699--702},
 title = {2）-④耳鼻科領域のMRSA感染(シンポジウム MRSA感染, 現状と対策, 第480回新潟医学会)},
 volume = {107},
 year = {1993}
}