@article{oai:niigata-u.repo.nii.ac.jp:00019950, author = {青木, 信樹}, issue = {8}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Aug}, note = {Clinical studies were performed in 508 cases with respiratory tract infections, from 1990 through 1991, at Shinrakuen Hospital. These cases consited of 255 pneumonias, 6 pulmonary abscesses, 222 secondary infections to chronic respiratory tract diseases, 11 pyothoraxes and 14 other infections. Causative organisms were unknown in 48.7% of the patients with pneumonia or pulmonary abscess, gram-positive cocci were isolated in 19.2% of them, gram-negative rods in 14.2%, and mixed infections in 15.3%. S.aureus was isolated in 23 patients (MRSA 14, MSSA 9 cases), and that (8.8%) was the most frequent organism causing pneumonia or pulmonary abscess. In chronic respiratory tract infections, gram-negative pathogens were dominant in causative organisms (35.1%), gram-positive cocci in 14.4%, mixed infections in 14.0%, and unknown in 36.5%. Major six organisms were P.aeruginosa (10.8%), S.pneumoniae (8.1%), S.aureus (5.9%), H.influenzae (5.9%), Haemophilus sp. (5.9%) and B.catarrhalis (4.1%). The mortality in pneumonia or pulmonary abscess with MRSA infection was 40.0% and that in chronic respiratory tract infection was 30.8%. The over all clinical effect was good in 25 patients (53.4%) poor in 21 with MRSA infection on pneumonia or pulmonary abscess. Bacteriologically, MRSA was eradicated in 8 patients (17.4%), decreased in 6, and unchanged in 32. From this study, β-lactam antibiotic combined with ABK or VCM was considered to be useful in the treatment of MRSA infection in respiratory tract.}, pages = {687--695}, title = {2)-②MRSA呼吸器感染症(シンポジウム MRSA感染, 現状と対策, 第480回新潟医学会)}, volume = {107}, year = {1993} }