{"created":"2021-03-01T06:24:50.936287+00:00","id":19947,"links":{},"metadata":{"_buckets":{"deposit":"29735032-0ac1-4b8d-b310-2afb8b7e1102"},"_deposit":{"id":"19947","owners":[],"pid":{"revision_id":0,"type":"depid","value":"19947"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00019947","sets":["453:456","471:537:538:1159"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Mechanisms of Antibiotic Resistance of Methicillin-Resistant Staphylococcus aureus : Review (Nosocomial Infections caused by Methicillin-Resistant Staphyllococcus aureus（MRSA）: The Present Problems and The Strategies for Prevention)"}]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1993-08","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"8","bibliographicPageEnd":"674","bibliographicPageStart":"672","bibliographicVolumeNumber":"107","bibliographic_titles":[{"bibliographic_title":"新潟医学会雑誌"},{"bibliographic_title":"新潟医学会雑誌","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Methicillin （DMPPC）-resistant Staphylococcus aureus （MRSA） is charactecteristic of resistance agaist not only DMPPC but other multiple antibiotics. The pattern of drug resistance is variable among MRSA strains, but DMPPC resistance is common. 1）DMPPC resistance of MRSA MRSA produces a specific enzyme named penicillin-binding protein 2'（PBP2'） which is not able to be detected from sensitive S.aureus. The protein production is inducible by β-lactam antibiotics. The property of the enzyme production is very stable because it is coded on a chromosomal gene, mecA. The resistance is temperature-sensitive and lost in acid condition. 2）Multiple drug resistance of MRSA Most of MRSA strains are β-lactamase-positive. In addition to β-lactam resistance, MRSA shows resistance to tetracylines and aminogycoside antibiotics with various levels and frequencies. The drug resistance depends on plasimids.","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"123627","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Shigeno, Naoya"}]}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟医学会"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00182415","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00290440","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"重野, 直也"}],"nameIdentifiers":[{"nameIdentifier":"123626","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-16"}],"displaytype":"detail","filename":"107(8)_672-674.pdf","filesize":[{"value":"477.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"107(8)_672-674.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/19947/files/107(8)_672-674.pdf"},"version_id":"46dc1855-b5a8-4b87-8036-f6bdf332b1cf"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"MRSA","subitem_subject_scheme":"Other"},{"subitem_subject":"penicillin-binding proteins","subitem_subject_scheme":"Other"},{"subitem_subject":"PBP2'","subitem_subject_scheme":"Other"},{"subitem_subject":"ペニシリン結合性蛋白","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"1）-①MRSAの耐性機構 : 綜説(シンポジウム MRSA感染, 現状と対策, 第480回新潟医学会)","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"1）-①MRSAの耐性機構 : 綜説(シンポジウム MRSA感染, 現状と対策, 第480回新潟医学会)"},{"subitem_title":"1）-①MRSAの耐性機構 : 綜説(シンポジウム MRSA感染, 現状と対策, 第480回新潟医学会)","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","1159"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-02-04"},"publish_date":"2016-02-04","publish_status":"0","recid":"19947","relation_version_is_last":true,"title":["1）-①MRSAの耐性機構 : 綜説(シンポジウム MRSA感染, 現状と対策, 第480回新潟医学会)"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:50:48.591071+00:00"}