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  1. 0 資料タイプ別
  2. 01 学術雑誌論文
  1. 070 農学部
  2. 10 学術雑誌論文
  3. 10 査読済論文

Pancreatic Weakness in Zucker Fatty Rats, a Genetic Obese Model

http://hdl.handle.net/10191/30616
http://hdl.handle.net/10191/30616
51d6a5e4-7b6f-46eb-98eb-29f750a60381
名前 / ファイル ライセンス アクション
9_23_2963-2968.pdf 9_23_2963-2968.pdf (321.5 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2014-12-01
タイトル
タイトル Pancreatic Weakness in Zucker Fatty Rats, a Genetic Obese Model
タイトル
言語 en
タイトル Pancreatic Weakness in Zucker Fatty Rats, a Genetic Obese Model
言語
言語 eng
キーワード
主題Scheme Other
主題 Diabetes
キーワード
主題Scheme Other
主題 pancreas
キーワード
主題Scheme Other
主題 streptozotocin
キーワード
主題Scheme Other
主題 Zf rat
キーワード
主題Scheme Other
主題 dysfunction
キーワード
主題Scheme Other
主題 weakness
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Ohta, Takeshi

× Ohta, Takeshi

WEKO 6504

Ohta, Takeshi

Search repository
Miyajima, Katsuhiro

× Miyajima, Katsuhiro

WEKO 6505

Miyajima, Katsuhiro

Search repository
Yamada, Takahisa

× Yamada, Takahisa

WEKO 6506

Yamada, Takahisa

Search repository
抄録
内容記述タイプ Abstract
内容記述 Pancreatic dysfunction is a pivotal factor on incidence and development of diabetes mellitus and especially, the pancreatic weakness is a key defect contributing to diabetes mellitus. In this study, we investigated the pancreatic weakness in obese Zucker Fatty (ZF) rats. Different doses of Streptozotocin (STZ) were administered to ZF rats and the biochemical and the pancreatic related parameters were examined. Wistar rats were used as control animals. Before STZ injection, ZF rats showed a tendency to increase of insulinogenic index as compared with that in Wistar rats but the disposition index in ZF rats was significantly decreased as compared with that in Wistar rats. Moreover, the islets of STZ-untreated ZF rats were larger and had irregular boundaries. ZF rats treated with STZ at a dose level of 20 mg kg-1 were diabetic within one week after the treatment whereas Wistar rats got the diabetic after 30 mg kg-1 STZ was received.
書誌情報 Journal of animal and veterinary advances
en : Journal of animal and veterinary advances

巻 9, 号 23, p. 2963-2968, 発行日 2010-12
出版者
出版者 Medwell Journals
ISSN
収録物識別子タイプ ISSN
収録物識別子 16805593
DOI
識別子タイプ DOI
関連識別子 info:doi/10.3923/javaa.2010.2963.2968
権利
権利情報 Copyright(C)2010 Medwell Journals
著者版フラグ
値 publisher
異版である
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 http://docsdrive.com/pdfs/medwelljournals/javaa/2010/2963-2968.pdf
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