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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第107巻第10号

大量輸血後の多発外傷患者における出血凝固異常および外傷後黄疸に関する検討

http://hdl.handle.net/10191/37745
http://hdl.handle.net/10191/37745
811907a3-929e-493c-a11d-bf553460d77e
名前 / ファイル ライセンス アクション
107(10)_896-910.pdf 107(10)_896-910.pdf (2.3 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2016-02-05
タイトル
タイトル 大量輸血後の多発外傷患者における出血凝固異常および外傷後黄疸に関する検討
タイトル
言語 en
タイトル 大量輸血後の多発外傷患者における出血凝固異常および外傷後黄疸に関する検討
言語
言語 jpn
キーワード
主題Scheme Other
主題 multiple injuries
キーワード
主題Scheme Other
主題 massive transfusion
キーワード
主題Scheme Other
主題 bleeding tendency
キーワード
主題Scheme Other
主題 dilutional thrombocytopenia
キーワード
主題Scheme Other
主題 disseminated intravascular coagulation(DIC)
キーワード
主題Scheme Other
主題 post-traumatic jaundice
キーワード
主題Scheme Other
主題 多発外傷
キーワード
主題Scheme Other
主題 大量輸血
キーワード
主題Scheme Other
主題 出血傾向
キーワード
主題Scheme Other
主題 希釈性血小板減少
キーワード
主題Scheme Other
主題 播種性血管内凝固症候群
キーワード
主題Scheme Other
主題 外傷後黄疸
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル Studies on Coagulation Abnormalities and Post-traumatic Jaundice in Patients of Multiple Injuries after Massive Transfusion
著者 吉川, 恵次

× 吉川, 恵次

WEKO 122900

吉川, 恵次

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佐藤, 一範

× 佐藤, 一範

WEKO 122901

佐藤, 一範

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本多, 忠幸

× 本多, 忠幸

WEKO 122902

本多, 忠幸

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斎藤, 憲

× 斎藤, 憲

WEKO 122903

斎藤, 憲

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著者別名
識別子 122904
識別子Scheme WEKO
姓名 Yoshikawa, Keiji
著者別名
識別子 122905
識別子Scheme WEKO
姓名 Sato, Kazunori
著者別名
識別子 122906
識別子Scheme WEKO
姓名 Honda, Tadayuki
著者別名
識別子 122907
識別子Scheme WEKO
姓名 Saito, Akira
抄録
内容記述タイプ Abstract
内容記述 The purpose of the present study is to clarify what is the most common mechanism of eliciting coagulation abnormalities in massively transfused trauma patients, and to clarify the relationship between such abnormalities and the development of post-traumatic jaundice. A retrospective analysis was made of the charts of 8 trauma patients (ISS: 18~36, median; 26.5) treated at Emergency and Critical Care Unit, Niigata University Hospital. i) Significant negative correlation between the nadir value of the blood platelet count (usually seen on the 2nd post-injury day) and the total replaced blood volume was observed. In addition, cumulative balance between the volume of administered fluid and urine during the time from injury to 6:00 am, 2nd post-injury day tended to negatively correlate with the nadir value. ii) Only slight prolongation of the PT, APTT was seen in patients receiving massive transfusion during the early post-injury day. iii) Specific parameters of DIC, such as FDP, TAT, D-Dimer etc., were markedly elevated in all patients transfused more than 10,000 ml. iv) Marked post-traumatic jaundice was observed in 3 out of 4 massively transfused patients, in whom prolonged shock after the injury and the DIC in the early post-injury period were commonly seen. Conclusion. 1) Bleeding tendency in post-traumatic patients after massive transfusion is mainly caused by dilutional thrombocytopenia (DT) and disseminated intravascular coagulation (DIC). Unlikely contribution of the dilutional coagulopathy (DC: due to the dilution of clotting factors by fluid infused) to the disorder is suggested. 2) Contribution of the prolonged shock during the immediate post-injury period to the profound post-traumatic jaundice in massively transfused patients was shown. Role of the DIC commonly seen in such patients in eliciting the jaundice has to be clarified.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 107, 号 10, p. 896-910, 発行日 1993-10
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
値 publisher
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