@article{oai:niigata-u.repo.nii.ac.jp:00019537, author = {安保, 徹}, issue = {2}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Feb}, note = {The existence of extrathymically differentiated T cells was recently demonstrated by us and other investigators. The subsequent studies revealed that the sits where such extrathymic T cells are differentiated include the hepatic sinusoids and intraepithelial sites in the intestine. Especially, extrathymic T cells generated in the liver appear even in the organs other than the liver when they are activated. They may act rationally as a surveillance system against abnormal self, and sometimes seem to induce certain autoimmune diseases when they are over-activated. In this study, we have investigated detailed sites of extrathymic T-cell differentiation in the liver and their subsequent movements by using normal mice, congenitally athymic nude mice and autoimmune MRL-lpr/lpr mice (human SLE model).}, pages = {83--90}, title = {胸腺外分化T細胞の増殖, 循環, 形態について}, volume = {108}, year = {1994} }