@article{oai:niigata-u.repo.nii.ac.jp:00019400,
 author = {田中, 正美 and 鈴木, 和夫 and 遠藤, 耕太郎 and 姉崎, 利治 and 丹野, 芳範 and 桑原, 武夫 and 佐藤, 修三 and 辻, 省次 and 栗田, 勇 and 岡田, 耕作 and 畠山, 悟 and 酒井, 靖夫 and 畠山, 勝義},
 issue = {4},
 journal = {新潟医学会雑誌, 新潟医学会雑誌},
 month = {Apr},
 note = {Two patients with Wernicke's encephalopathy after glucose and electrolyte infusion without vitamins were described. Both patients showed consciousness disturbance, complete ophthalmoplegia and areflexia of bilateral lower extremities. The characteristic neurological findings as well as MR findings such as lesions at dorsal medial nuclei of the thalamus and periaqueductal regions enabled early diagnosis of the disease. Because thiamine is required in glucose metabolism as a coenzyme, carbohydrate loading in the presence of marginal thiamine storage can result in the development of Wernicke's encephalopathy. It should be noted that Wernicke's encephalopathy can easely be induced by prolonged intravenous glucose infusion without vitamines. Wernicke's encephalopathy in such cases should be prevented by appropriate supplementation of vitamines, which has some confilict with of current system of health insurance.},
 pages = {267--270},
 title = {3) 糖質輸液後に発生したWernicke脳症(シンポジウム 保険医療をめぐる諸問題, 第489回新潟医学会総会）},
 volume = {108},
 year = {1994}
}