@article{oai:niigata-u.repo.nii.ac.jp:00019252, author = {藤田, 俊夫 and 相沢, 正樹 and 山添, 優 and 和泉, 徹 and 柴田, 昭 and 服部, 晃 and 林, 純一 and 江口, 昭治}, issue = {7}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Jul}, note = {The present study was aimed to elucidate the effect of antiplatelet therapy on patency of saphenous vein graft after aorto-coronary bypass surgery. We divided the 96 patients who underwent aorto-coronary bypass surgery into two groups: GATS (Graft Aspirin Ticlopidine Study) group and control group. And the occlusion rate was assessed both at the time of one month and 12 months after bypass surgery. All patients received warfarin, and the patients in GATS group received aspirin (10~50mg) and ticlopidine (100~200mg). The patients in control group received only warfarin. In GATS group, the early occlusion rate was 14.6% and the late occlusion rate was 28.8%. On the other hand, the early occlusion rate was 19.2% and the late occlusion rate was 28.8% in control group. There was no significant difference in the occlusion rate between GATS group and control group. In patients whose graft flow was under 50ml/min, the occlusion rate in GATS group was 10.8%, but in control group was 32.1% at the time of one month. These results indicate that antiplatelet therapy after A-C bypass surgery may have no effect on whole occlusion rate, but may have a little effect on the occlusion rate in low graft flow group. It may be important that when we should start the antiplatelet therapy after aortocoronary bypass surgery.}, pages = {532--539}, title = {新しい抗血小板療法による冠動脈バイパス術後の閉塞防止の研究 : 第三報 : 長期成績および総括}, volume = {108}, year = {1994} }