@article{oai:niigata-u.repo.nii.ac.jp:00019251, author = {林, 純一 and 小熊, 文昭 and 中沢, 聡 and 江口, 昭治 and 丸山, 行夫 and 山添, 優 and 和泉, 徹 and 柴田, 昭 and 服部, 晃}, issue = {7}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Jul}, note = {In order to clarify the benefit of treatment using ticlopidine with low-dose aspirin on saphenous vein graft patency after aorto-coronary bypass, a randomized study was performed on 135 patients who were operated between January 1987 and March 1991 at Niigata University Hospital or Niigata Kobari Hospital. Among them, 38 patients were excluded from the study because they didn't meet the protocol requirements. Subjects were divided into antiplatelet therapy (AT) group (n=58) and control group (n=39). Saphenous vein graft patency was evaluated by coronary angiography 1 month after the operation. Although the overall graft patency rate was 86.5% in the AT group and 81.4% in the control group (N.S.), higher patency rate were noticed in the AT group than those in the control group in grafts on the left anterior decending and the right coronary arteries. The present study suggest that the antiplatelet treatment will play a favorable role on maintaining the graft patency.}, pages = {527--531}, title = {新しい抗血小板療法による冠状動脈バイパス術後の閉塞防止の研究 : 第二報 : 外科治療と早期成績}, volume = {108}, year = {1994} }