{"created":"2021-03-01T06:24:04.816785+00:00","id":19242,"links":{},"metadata":{"_buckets":{"deposit":"756050b3-fa78-46ee-b2a5-d604cc6ddeb7"},"_deposit":{"id":"19242","owners":[],"pid":{"revision_id":0,"type":"depid","value":"19242"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00019242","sets":["453:456","471:537:538:1148"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Basal Ganglia in Aging and Dementia"}]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1994-07","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"7","bibliographicPageEnd":"480","bibliographicPageStart":"475","bibliographicVolumeNumber":"108","bibliographic_titles":[{"bibliographic_title":"新潟医学会雑誌"},{"bibliographic_title":"新潟医学会雑誌","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The neostriatum, nucleus accumbens and basal nucleus of meynert (bnM) in Alzheimer's disease (AD), progressive supranuclear palsy (PSP) and parkinsonism-dementia complex of Guam (GuamPDC) were examined immunohistologically, ultrastructurally, quantitatively and topographically. Compaired to neurologically normal controls, the number of large neurons was reduced by approximately 65% in the caudate nucleus and putamen in these diseases and especially, in AD and GuamPDC, by more than 90% in the nucleus accumbens. The decreased number of large neurons in the neostriatum was significantly correlated to that in the bnM in AD and GuarnPDC, but not in PSP. The remaining large neurons in the neostriatum and nucleus accumbens of these three diseases contained neurofibrillary tangles (NFTs). The NFTs were composed varying amounts of 21-to 25-nm wide paired helical filaments admixed with straight tubules (STs) in AD and GuamPDC, and composed mainly of STs in PSP. Extremely severe loss of large neurons in the nucleus accumbens in AD and GuamPDC may be linked to marked degeneration of the limbic and ventral tegmental areas and nucleus dorsal raphe.","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"119870","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Oyanagi, Kiyomitsu"}]},{"nameIdentifiers":[{"nameIdentifier":"119871","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Ikuta, Fusahiro"}]}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟医学会"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00182415","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00290440","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"小柳, 清光"}],"nameIdentifiers":[{"nameIdentifier":"119868","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"生田, 房弘"}],"nameIdentifiers":[{"nameIdentifier":"119869","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-08"}],"displaytype":"detail","filename":"108(7)_475-480.pdf","filesize":[{"value":"1.9 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"108(7)_475-480.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/19242/files/108(7)_475-480.pdf"},"version_id":"83036ed7-fc0a-4c15-a7ee-bfbb5eed0a70"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"neostriatum","subitem_subject_scheme":"Other"},{"subitem_subject":"nucleus accumbens","subitem_subject_scheme":"Other"},{"subitem_subject":"Alzheimer's disease","subitem_subject_scheme":"Other"},{"subitem_subject":"progressive supranuclear palsy","subitem_subject_scheme":"Other"},{"subitem_subject":"parkinsonism-dementia complex of Guam","subitem_subject_scheme":"Other"},{"subitem_subject":"線条体","subitem_subject_scheme":"Other"},{"subitem_subject":"側坐核","subitem_subject_scheme":"Other"},{"subitem_subject":"アルツハイマー病","subitem_subject_scheme":"Other"},{"subitem_subject":"進行性核上性麻痺","subitem_subject_scheme":"Other"},{"subitem_subject":"グアム島パーキンソン・痴呆症","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"加齢および痴呆と基底核","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"加齢および痴呆と基底核"},{"subitem_title":"加齢および痴呆と基底核","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","1148"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-02-17"},"publish_date":"2016-02-17","publish_status":"0","recid":"19242","relation_version_is_last":true,"title":["加齢および痴呆と基底核"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:50:12.504484+00:00"}