@article{oai:niigata-u.repo.nii.ac.jp:00018896, author = {田宮, 洋一 and 小野, 一之 and 島影, 尚弘 and 佐藤, 賢治 and 佐藤, 信昭 and 松尾, 仁之 and 畠山, 勝義}, issue = {11}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Nov}, note = {In order to study onset time and site of bone disease after gastrectomy, bone mineral content (BMC) of the third lumbar spine and distal radius was measured in 114 male patients of their 50s and 60s with gastric cancer (stage 1 or 2). 52 patients were before gastrectomy (group 0). Other 62 patients were after subtotal gastrectomy and Billroth 1 reconstruction and divided into four groups according with postoperative period, (1 year (group 1), 2 year (group 2), 3 to 10 year (grop 3), and over 11 year (group 4) after operation each other). BMC of the third lumbar spine was measured by DPA and that of the distal radius was done by SPA. Serum calcium, phosphorus, bone alkaline phosphatase and osteocalcine wewe also measured. 「results」1. The incidence of patients with low BMC of lumbar spine was significantly higher in group 2, 3, 4 than in group 0, and that with low BMC of dsital radius was significantly higher than in group 3 than in group 0. 2. In all patients after operation, incidence of low BMC of lumbar spine was 43 %, that of distal radius was 35%, and that of both site was 22 %. All the incidence became significantyly higher than those before operation. 3. Serum phosphorus was lower and bone alkaline phosphatase was higher significantly in patients with low BMC of distal radius than thsose with normal BMC of both sites and those with low BMC of lumbar spine associated with normal BMC of distal radius. These results showed that bone disease after gastrectomy occured within 2 years after operation, and two type of bone disease might exis after gastrectomy, -that is, one type would preferantially involve the spine, and another one woud impair the limb.}, pages = {826--832}, title = {5)胃切除後骨病変の発症時期と部位(シンポジウム 骨粗鬆症の病態・治療・予防, 第493回新潟医学会)}, volume = {108}, year = {1994} }