{"created":"2021-03-01T06:22:56.250157+00:00","id":18197,"links":{},"metadata":{"_buckets":{"deposit":"38ad78ec-ffa2-4276-bbcb-1c2a189c0cf8"},"_deposit":{"id":"18197","owners":[],"pid":{"revision_id":0,"type":"depid","value":"18197"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00018197","sets":["453:456","471:537:538:1131"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Lipid Structure in the Water Permeability Barrier of Human Epidermis"}]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1996-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"99","bibliographicPageStart":"95","bibliographicVolumeNumber":"110","bibliographic_titles":[{"bibliographic_title":"新潟医学会雑誌"},{"bibliographic_title":"新潟医学会雑誌","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"In any living system, control of water permeability is essential for survival. This review begins with an overview of the vast amount of work that has led to a greater understanding of the mechanisms of water permeability barrier (PB) of the stratum corneum, including the nature of stratum corneum lipids, and specifically examines the essential role of ceramides, together with the role of linoleate. The final parts of the review summarized our study of dry skin in atopic dermatitis (AD). In the study, a significant decrease in proportion of ceramide 1, which is a carrier of linoleate responsible for PB function and decreased levels of esterified linoleate of ceramide 1 were observed in AD patients.","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"114045","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Yamamoto, Ayako"}]}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟医学会"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00182415","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00290440","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"山本, 綾子"}],"nameIdentifiers":[{"nameIdentifier":"114044","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-08"}],"displaytype":"detail","filename":"110(3)_95-99.pdf","filesize":[{"value":"820.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"110(3)_95-99.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/18197/files/110(3)_95-99.pdf"},"version_id":"2f41b6ab-05d3-4ea6-aca5-e82e4230874d"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"water permeability barrier","subitem_subject_scheme":"Other"},{"subitem_subject":"ceramide 1","subitem_subject_scheme":"Other"},{"subitem_subject":"linoleate","subitem_subject_scheme":"Other"},{"subitem_subject":"dry skin","subitem_subject_scheme":"Other"},{"subitem_subject":"atopic dermatitis","subitem_subject_scheme":"Other"},{"subitem_subject":"乾燥性皮膚","subitem_subject_scheme":"Other"},{"subitem_subject":"アトピー性皮膚炎","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"皮膚のWater Permeability Barrierと脂質構造について","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"皮膚のWater Permeability Barrierと脂質構造について"},{"subitem_title":"皮膚のWater Permeability Barrierと脂質構造について","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","1131"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-08-02"},"publish_date":"2016-08-02","publish_status":"0","recid":"18197","relation_version_is_last":true,"title":["皮膚のWater Permeability Barrierと脂質構造について"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:49:24.157507+00:00"}