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Scavenger receptors are a trimeric glycoprotein mediating endocytosis of chemically modified low density lipoproteins (LDL). The receptors were detected specifically in macrophages in various tissues by immunohistochemistry using anti-bovine scavenger receptor monoclonal antibody IgG-D2, although hepatic sinusoidal cells are known to incorporate modified LDL actively. In contrast, scavenger receptor protein was detected both in Kupffer cells and endothelial cells of the hepatic sinusoid and lymphatic sinus by immunohistochemistry using anti-bovine scavenger receptor antibody IgG-D1 and anti-murine scavenger receptor antibody 2F8. In situ hybridization demonstrated the expression of scavenger receptor mRNA in Kupffer cells and sinusoidal endothelial cells. Scavenger receptors were not expressed in endothelial cells of other tissues than the liver and lymph nodes. These findings indicate that scavenger receptors are expressed both in macrophages and specific endothelial cells and that endothelial cells in various tissues constitute heterogeneous populations with regard to lipoprotein metabolism.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "\u8457\u8005\u5225\u540d", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "113457", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Naito, Makoto"}]}, {"nameIdentifiers": [{"nameIdentifier": "113458", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Takatsuka, Hisakazu"}]}, {"nameIdentifiers": [{"nameIdentifier": "113459", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Hasegawa, Go"}]}, {"nameIdentifiers": [{"nameIdentifier": "113460", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Ito, Shigeo"}]}, {"nameIdentifiers": [{"nameIdentifier": "113461", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Kodama, Tatsuhiko"}]}]}, 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