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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第110巻第6号

6) マクロファージと内皮細胞におけるスカベンジャー受容体の発現(シンポジウム 血管細胞生物学の進歩, 第517回新潟医学会)

http://hdl.handle.net/10191/43115
http://hdl.handle.net/10191/43115
e02fac9d-ad7d-4ee6-b089-e0c38831c62c
名前 / ファイル ライセンス アクション
110(6)_216-227.pdf 110(6)_216-227.pdf (3.4 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2016-08-08
タイトル
タイトル 6) マクロファージと内皮細胞におけるスカベンジャー受容体の発現(シンポジウム 血管細胞生物学の進歩, 第517回新潟医学会)
タイトル
言語 en
タイトル 6) マクロファージと内皮細胞におけるスカベンジャー受容体の発現(シンポジウム 血管細胞生物学の進歩, 第517回新潟医学会)
言語
言語 jpn
キーワード
主題Scheme Other
主題 scavenger receptor
キーワード
主題Scheme Other
主題 LDL receptor
キーワード
主題Scheme Other
主題 macrophages
キーワード
主題Scheme Other
主題 endothelial cells
キーワード
主題Scheme Other
主題 immunohistochemistry
キーワード
主題Scheme Other
主題 スカベンジャー受容体
キーワード
主題Scheme Other
主題 LDL 受容体
キーワード
主題Scheme Other
主題 マクロファージ
キーワード
主題Scheme Other
主題 内皮細胞
キーワード
主題Scheme Other
主題 免疫組織化学
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル Expression of Scavenger Receptors in Macrophages and Endothelial Cells (Recent Topics in Vascular Biology)
著者 内藤, 眞

× 内藤, 眞

WEKO 113452

内藤, 眞

Search repository
高塚, 尚和

× 高塚, 尚和

WEKO 113453

高塚, 尚和

Search repository
長谷川, 剛

× 長谷川, 剛

WEKO 113454

長谷川, 剛

Search repository
伊藤, 重雄

× 伊藤, 重雄

WEKO 113455

伊藤, 重雄

Search repository
児玉, 龍彦

× 児玉, 龍彦

WEKO 113456

児玉, 龍彦

Search repository
著者別名
識別子 113457
識別子Scheme WEKO
姓名 Naito, Makoto
著者別名
識別子 113458
識別子Scheme WEKO
姓名 Takatsuka, Hisakazu
著者別名
識別子 113459
識別子Scheme WEKO
姓名 Hasegawa, Go
著者別名
識別子 113460
識別子Scheme WEKO
姓名 Ito, Shigeo
著者別名
識別子 113461
識別子Scheme WEKO
姓名 Kodama, Tatsuhiko
抄録
内容記述タイプ Abstract
内容記述 In order to clarify the expression and tissue distribution of scavenger receptors, we have performed immunohistochemical and immunoelectron microscopical studies as well as in situ hybridization. Scavenger receptors are a trimeric glycoprotein mediating endocytosis of chemically modified low density lipoproteins (LDL). The receptors were detected specifically in macrophages in various tissues by immunohistochemistry using anti-bovine scavenger receptor monoclonal antibody IgG-D2, although hepatic sinusoidal cells are known to incorporate modified LDL actively. In contrast, scavenger receptor protein was detected both in Kupffer cells and endothelial cells of the hepatic sinusoid and lymphatic sinus by immunohistochemistry using anti-bovine scavenger receptor antibody IgG-D1 and anti-murine scavenger receptor antibody 2F8. In situ hybridization demonstrated the expression of scavenger receptor mRNA in Kupffer cells and sinusoidal endothelial cells. Scavenger receptors were not expressed in endothelial cells of other tissues than the liver and lymph nodes. These findings indicate that scavenger receptors are expressed both in macrophages and specific endothelial cells and that endothelial cells in various tissues constitute heterogeneous populations with regard to lipoprotein metabolism.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 110, 号 6, p. 216-227, 発行日 1996-06
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
値 publisher
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