{"created":"2021-03-01T06:22:41.254193+00:00","id":17967,"links":{},"metadata":{"_buckets":{"deposit":"4f350f42-15f8-47d8-8f84-14bd6aba6782"},"_deposit":{"id":"17967","owners":[],"pid":{"revision_id":0,"type":"depid","value":"17967"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00017967","sets":["453:456","471:537:538:1127"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"The Sort and Portion of Malignant Transformation in Gastric Adenoma : By p53 and Ki-67 Immunostaing"}]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1996-08","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"8","bibliographicPageEnd":"347","bibliographicPageStart":"337","bibliographicVolumeNumber":"110","bibliographic_titles":[{"bibliographic_title":"新潟医学会雑誌"},{"bibliographic_title":"新潟医学会雑誌","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The aim of this study was to elucidate what sort of gastric adenoma transforms into malignancy and where cancer develops in adenomatous tubule. The object was 111 gastric adenomas and 10 carcinoma arising in adenoma. p53 and Ki-67 immunostaing was performed for objective detection of small foci of microscopic carcinoma. Malignant transformation was found only in adenoma of high-grade cytological atypia and of 19mm or more in size. The rate was 8.3% (10/121) in total, 0% (0/71) in tumors less than 10mm, 8.7% (2/23) in 10≦x<20mm tumors, and 29.2% (8/27) in 20≦x tumors. Microscopic cancer was found in the proliferative zone (superficial layer) of adenomatous tubules by p53 immunostaing. The cancer tissue was of low-grade in cytological atypia, and cancer cells were Ki-67 positive. Then, cancer cells extended downwards along the adenomatous tubules. This is the first report which objectively verified these processes by p53 and Ki-67 immunostaing.","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"112786","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Maejima, Takehito"}]}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟医学会"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00182415","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00290440","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"前島, 威人"}],"nameIdentifiers":[{"nameIdentifier":"112785","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-08"}],"displaytype":"detail","filename":"110(8)_337-347.pdf","filesize":[{"value":"3.7 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"110(8)_337-347.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/17967/files/110(8)_337-347.pdf"},"version_id":"9a854ae3-b3a0-44d8-9887-cefcc05c2808"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"gastric adenoma","subitem_subject_scheme":"Other"},{"subitem_subject":"p53 immunostaining","subitem_subject_scheme":"Other"},{"subitem_subject":"Ki-67 immunostaining","subitem_subject_scheme":"Other"},{"subitem_subject":"cancer in adenoma","subitem_subject_scheme":"Other"},{"subitem_subject":"胃腺腫","subitem_subject_scheme":"Other"},{"subitem_subject":"p53 免疫染色","subitem_subject_scheme":"Other"},{"subitem_subject":"Ki-67 免疫染色","subitem_subject_scheme":"Other"},{"subitem_subject":"腺腫内癌","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"胃腺腫の癌化率と癌の形態発生 : p53とKi-67免疫染色からみて","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"胃腺腫の癌化率と癌の形態発生 : p53とKi-67免疫染色からみて"},{"subitem_title":"胃腺腫の癌化率と癌の形態発生 : p53とKi-67免疫染色からみて","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","1127"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-08-19"},"publish_date":"2016-08-19","publish_status":"0","recid":"17967","relation_version_is_last":true,"title":["胃腺腫の癌化率と癌の形態発生 : p53とKi-67免疫染色からみて"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:49:16.691995+00:00"}