@article{oai:niigata-u.repo.nii.ac.jp:00017471,
 author = {吉谷, 克雄 and 江口, 昭治},
 issue = {4},
 journal = {新潟医学会雑誌, 新潟医学会雑誌},
 month = {Apr},
 note = {Experimental cervical tracheal replacement using Marlex mesh or modified Nevile's prosthesis was performed in 29 mongrel dogs. Animals were divided into five groups. In group 1, 7 dogs received tracheal prostheses composed of Marlex polyethylene mesh, previously made air-tight with autologous fibrocollagen tissue. In group 2, 10 dogs received tracheal prostheses made of Marlex polyethylene mesh with Marlex polypropylene mesh inside, previously made air-tight with autologous fibrocollagen tissue. In group 3, 2 dogs received Modified Neville's prostheses wrapped circumferentially with Marlex polypropylene mesh. In group 4, 6 dogs received modified Neville's prostheses wrapped circumierentially with sewing ring made of Marlex polypropylene mesh with autologous fibrocollagen tissue. In group 5, 4 dogs received modified Neville's prostheses with sewing ring made of Marlex polypropylene mesh and fibrin glue. In group 1, stenosis of the lumen occured in a large number of animals due to overgrowth of granulation tissue at the anastomotic site. In contrast, in group 2, formation of granulation tissue at the anastomotic site was delayed, and partial epithelization of the inner surface was obtained in five of the ten dogs. However, only one case was successful, with the animal which surviving 49 months after replacement, and obtaining complete epithelization and no stenosis. In groups 3, 4, and 5, the complication of prosthetic migration was prevented, but infection and formation of granulation tissue often occurred at the anastomotic site. The results indicate that neovascular organization of the porous-type prosthesis at the time of tracheal replacement was important to avoid the formation of granulation tissue, and to induce epithelization. The non-porous prosthesis（modified Neville's prosthesis）did not prevent the formation of granulation tissue at the anastomotic site. Further investigation is necessary to prove the usefulness of new materials for this procedure is necessary.},
 pages = {228--241},
 title = {Marlex Meshおよび改良型Neville人工気管を用いた人工気管の実験的研究},
 volume = {111},
 year = {1997}
}