@article{oai:niigata-u.repo.nii.ac.jp:00017415, author = {星名, 秀行 and 大橋, 靖 and 鶴巻, 浩 and 長島, 克弘}, issue = {5}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {May}, note = {Unresectable advanced or recurrent head and neck cancers have, since 1986, been treated by thermo-radio-chemotherapy(TRC)in our department. The results of TRC applied to 27 lesions in 21 patients are reported, and compared with the results of treatment with radiochemotherapy(RC)for 36 lesions in 30 patients. Twenty-seven lesions were treated with 3 heating systems(13 with a radiofrequency system, 12 with a microwave system and 2 with a radiofrequency interstitial system). Hyperthermia was performed for a total of 2 to 20 times(mean:9.4 times). A temperature exceeding 42℃ was attained in 209(82%)of 255 treatments. The mean total doses of irradiation were 54 Gy in the TRC group, and 57 Gy in the RC group. In the TRC group, 7(25.9%)of the 27 lesions treated showed a complete response(CR), 14(51.9%)a partial response(PR)and 6(22.2%)no change(NC), and the response rate(CR plus PR)was 77.8%. In the RC group, 6(16.7%)of the 36 lesions treated showed a CR, 16(44.4%)a PR and 14(38.9%)NC, and the response rate was 61.1%. The 5-year cumulative local control rate was 50.6% in the TRC group, and 20.4% in the RC group. In conclusion, TRC is an effective treatment for head and neck cancer.}, pages = {289--294}, title = {2)頭頸部癌に対する温熱・放射線・化学療法 : 10年間 21症例 27病巣(シンポジウム 癌の温熱療法 : 各科領域における現状, 第519回新潟医学会シンポジウム)}, volume = {111}, year = {1997} }