@article{oai:niigata-u.repo.nii.ac.jp:00016794, author = {高野, 諭 and 工藤, 路子 and 鈴木, 正孝 and 丸山, 雄一郎}, issue = {4}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Apr}, note = {Long term LDL apheresis therapy was performed in a case of homozygous familial hypercholesterolemia. Patient had xanthoma at newborn age and at the age of five years his cholesterol level was showed 783 mg/dl. Plasma exchange therapy was started at 9 years old and continued for 4 years. LDL apheresis therapy was begun at the age of 13 years, but he complained severe anginal pain at next year and his CAG showed two vessel disease include left main coronary trunk and right coronary artery stenosis. Immediately CABG to LAD operation was down used saphenous vein, after operation he was free fron anginal pain. Deterioration of the native coronary and graft stenosis was not found by the follow up study of CAG. At 24 years old he visited to our clinic for pneumonia and severe heart failure, and in spite of aggressive therapy patient died for congestive heart failure.}, pages = {194--198}, title = {長期間LDLアフェレーシス療法を施行した家族性高コレステロール血症ホモ接合体の1例}, volume = {112}, year = {1998} }