@article{oai:niigata-u.repo.nii.ac.jp:00016676, author = {出塚, 次郎}, issue = {6}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Jun}, note = {In order to study the animal model of polymyositis, a CD4 positive and CD8 negative T cell line was established from SJL/J mice immunized with a rabbit crude myosin fraction. The T cell line reacted with the crude myosin fraction but not with the purified six major muscular constitutional proteins. The histological examination showed myositis in SJL/J mice at 3 weeks after the injection of the T cell line. This is the first report that CD4 positive T cells reacting with crude muscle protein can cause myositis in mice.}, pages = {351--356}, title = {SJL/JマウスにおけるT細胞惹起性筋炎}, volume = {112}, year = {1998} }