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  1. 0 資料タイプ別
  2. 01 学術雑誌論文
  1. 070 農学部
  2. 10 学術雑誌論文
  3. 10 査読済論文

Newly Established Low Seizure Susceptible and Seizure-Prone Inbred Strains of Mongolian Gerbil

http://hdl.handle.net/10191/25127
http://hdl.handle.net/10191/25127
eb93c196-aa4f-48f6-8a91-210da6b3545e
名前 / ファイル ライセンス アクション
52_2_169-172.pdf 52_2_169-172.pdf (28.7 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2014-02-12
タイトル
タイトル Newly Established Low Seizure Susceptible and Seizure-Prone Inbred Strains of Mongolian Gerbil
タイトル
言語 en
タイトル Newly Established Low Seizure Susceptible and Seizure-Prone Inbred Strains of Mongolian Gerbil
言語
言語 eng
キーワード
主題Scheme Other
主題 epilepsy
キーワード
主題Scheme Other
主題 gerbil
キーワード
主題Scheme Other
主題 inbred strain
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 FUJISAWA, Nobuyoshi

× FUJISAWA, Nobuyoshi

WEKO 4807

FUJISAWA, Nobuyoshi

Search repository
MAEDA, Yoshitaka

× MAEDA, Yoshitaka

WEKO 4808

MAEDA, Yoshitaka

Search repository
YAMAMOTO, Yoshitaka

× YAMAMOTO, Yoshitaka

WEKO 4809

YAMAMOTO, Yoshitaka

Search repository
SATO, Norimitsu L.

× SATO, Norimitsu L.

WEKO 4810

SATO, Norimitsu L.

Search repository
NIIMURA, Sueo

× NIIMURA, Sueo

WEKO 4811

NIIMURA, Sueo

Search repository
抄録
内容記述タイプ Abstract
内容記述 Two inbred strains of the Mongolian gerbil with different phenotypes in seizure behaviour and coat color were newly established. LSAG/Nu has low seizure susceptibility and albino phenotypes, whereas SPBG/Nu has seizure-prone and black coat color phenotypes. LSAG was compared with SPBG as to seizure incidence and grade. Mean ages at seizure onset of LSAG and SPBG were 6 and 3 months, respectively. Seizure incidences in over 9 months old LSAG and SPBG gerbils were 37.3% (66/177) and 95.2% (118/124), respectively. LSAG has a significantly lower incidence (p<0.001) and grade (p<0.001) of seizures than SPBG. Only a few seizing LSAG gerbils exhibited myoclonus to tonic-clonic seizure progression. These results suggest that LSAG has some mechanisms which delay the onset of seizures and prevent them from becoming serious. Both strains of gerbils can be expected to be useful animal models for the study of human idiopathic generalized epilepsy.
書誌情報 Experimental animals
en : Experimental animals

巻 52, 号 2, p. 169-172, 発行日 2003-12
出版者
出版者 日本実験動物学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 13411357
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA11032321
DOI
識別子タイプ DOI
関連識別子 info:doi/10.1538/expanim.52.169
権利
権利情報 本文データは学協会の許諾に基づきJ-Stageから複製したものである
著者版フラグ
値 publisher
異版である
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 https://www.jstage.jst.go.jp/article/expanim/52/2/52_2_169/_pdf
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