@article{oai:niigata-u.repo.nii.ac.jp:00016267, author = {中村, 裕一}, issue = {12}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Dec}, note = {To elusidate the reation between coronary risk factors and development of coronary atherosclerosis, we investigated 1102 patients who underwent coronary angiography in Niigata Unioversity Hospital. Coronary angiographic findigs and information of coronary risk factors were obtained from medical records. Development and severity of CAD:In patient with CAD, prevalence rate of hypertension, dyslipidemia, smoking and diabetes mellitus were significantly higher than those without CAD (hypertension 44.5% vs 57.5%, dyslipidemia 30.6% vs 43.8%, smoking 48.5% vs 61.6%, diabetes mellitus 15.9% vs 37.1%). Prevalence rates of risk factors increased according to the severity of CAD. Progression of CAD:We compared risk factor control rate between progression group and non-progression group. Control rate of blood sugar in progression group was significantly lower than that in non-progression group (79.2% vs 89.2% p<0.05). The progression rate of those who had no risk factor during observarion period was only 14%, while the rate of those who had more than 1 risk factors were over 40%. Restenosis after coronary angioplasty:Restenosis rate of smoker was significantly higher than that of non-smoker (54.2 vs 34.2% p<0.01). Coronary risk factors have close relation in development and progression of CAD and strict risk factor control is needed to prevent progression and restenosis after coronary angioplasty.}, pages = {765--769}, title = {4)虚血性心疾患の発症・進展と危険因子 : 当院の現況(シンポジウム 高脂血症, 動脈硬化をめぐって, 第540回新潟医学会)}, volume = {112}, year = {1998} }