{"created":"2021-03-01T06:20:48.107743+00:00","id":16226,"links":{},"metadata":{"_buckets":{"deposit":"aa1a53c1-9e37-4463-9134-b2060d704fac"},"_deposit":{"id":"16226","owners":[],"pid":{"revision_id":0,"type":"depid","value":"16226"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00016226","sets":["453:456","471:537:538:1100"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"High Intensity Transient Signals (HITS) During Open Heart Surgery-Relationship Between HITS Frequency and Micro-Bubbles"}]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1999-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"54","bibliographicPageStart":"45","bibliographicVolumeNumber":"113","bibliographic_titles":[{"bibliographic_title":"新潟医学会雑誌"},{"bibliographic_title":"新潟医学会雑誌","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Purpose:High intensity transient signals (HITS) by transcranial Doppler (TCD) have been reported to reflect micro-embolus in cerebral artery. HITS are frequently detected during cardiopulmonary bypass (CPB), however the clinical significance of HITS during CPB is still unknown. In experiments, micro-bubble presented high frequency HITS more than 400 Hz. The present study is designed to elucidate how many HITS with more than 400 Hz were detected during CPB and whether CPB event is associated with the number of those HITS. Methods:Subjects were 4 patients with mitral valve disease and 2 with left atrial myxoma. All the patients underwent open heart surgery with CPB. HITS were detected by TC2020 with 2.0 MHz pulsed Doppler at the middle cerebral artery. Transesophageal echocardiography was undertaken during the surgery and cardiac and aortic microbubbles were observed. Results:The number of HITS during CPB was 1707±1392 (mean±SD). 88.1% of the HITS during CPB had more than 400 Hz. The HITS count rate at the aortic unclamp (105±107/min) and at the bignning of re-beating (117±139/min) was significantly higher (p<0.001). When micro-bubbles were observed by TEE, HITS with high frequency were detected. The ratio of HITS with more than 400 Hz was 88% at the aortic unclamp, 88% at the biginning of re-beating, respectively. Conclusion:Many HITS were detected during CPB. Most of them had more than 400 Hz which may reflect micro-bubbles. The ratio of HITS with more than 400 Hz increased after reperfusion from the heart. HITS frequency analysis may differentiate solid micro-embolus during which may occur cerebral embolism. Therfore HITS frequency analysis may be useful for detecting solid micro-embulus among many HITS during CPB.","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"103514","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Liu, Wei"}]}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟医学会"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00182415","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00290440","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"劉, 維"}],"nameIdentifiers":[{"nameIdentifier":"103513","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-07"}],"displaytype":"detail","filename":"113(1)_45-54.pdf","filesize":[{"value":"1.4 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"113(1)_45-54.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/16226/files/113(1)_45-54.pdf"},"version_id":"cb9b8c47-e6de-4aa9-9518-334e4a08afe8"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"HITS","subitem_subject_scheme":"Other"},{"subitem_subject":"TCD","subitem_subject_scheme":"Other"},{"subitem_subject":"CPB","subitem_subject_scheme":"Other"},{"subitem_subject":"frequency","subitem_subject_scheme":"Other"},{"subitem_subject":"micro-bubble","subitem_subject_scheme":"Other"},{"subitem_subject":"経頭蓋超音波","subitem_subject_scheme":"Other"},{"subitem_subject":"体外循環","subitem_subject_scheme":"Other"},{"subitem_subject":"周波数","subitem_subject_scheme":"Other"},{"subitem_subject":"微小気泡","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"開心術時における経頭蓋超音波検査によるHigh Intensity Transient Signals(HITS) : 特にHITSの周波数と微小気泡との関係についての研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"開心術時における経頭蓋超音波検査によるHigh Intensity Transient Signals(HITS) : 特にHITSの周波数と微小気泡との関係についての研究"},{"subitem_title":"開心術時における経頭蓋超音波検査によるHigh Intensity Transient Signals(HITS) : 特にHITSの周波数と微小気泡との関係についての研究","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","1100"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-02-16"},"publish_date":"2017-02-16","publish_status":"0","recid":"16226","relation_version_is_last":true,"title":["開心術時における経頭蓋超音波検査によるHigh Intensity Transient Signals(HITS) : 特にHITSの周波数と微小気泡との関係についての研究"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:47:46.013150+00:00"}