{"_buckets": {"deposit": "812b615d-af37-4b39-a873-63d612cd49dd"}, "_deposit": {"id": "16219", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "16219"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00016219"}, "item_7_alternative_title_1": {"attribute_name": "\u305d\u306e\u4ed6\u306e\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_alternative_title": "Development of Fatty Acid Derivatives Labeled with Short-lived Positron Emitters and Its Application for PET Studies"}]}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1999-01", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1", "bibliographicPageEnd": "13", "bibliographicPageStart": "1", "bibliographicVolumeNumber": "113", "bibliographic_titles": [{"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c"}, {"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "For the development of myocardial imaging tracers in PET (positron emission computed tomography) studies, new labeling methods and new radiopharmaceuticals of [^\u003c11\u003eC]/[^\u003c18\u003eF] labeled fatty acid derivatives were investigated. In [^\u003c11\u003eC] labeling of fatty acids, a new chemical approach to the preparation of [1-^\u003c11\u003eC] fatty acids from [^\u003c11\u003eC] HCN was developed. This method has some advantages, such as no requirement of absolutely anhydrous solvent, easy [^\u003c11\u003eC] labeling using an extremely small amount of substrate, and good reproducibility. From these advantages, it has been shown that this new approach is one of efficient synthetic methods of [1-^\u003c11\u003eC] labeled fatty acids for use in routine PET studies. While, in [^\u003c18\u003eF] labeling of fatty acids, 5-methyl-17-[^\u003c18\u003eF] fluoroheptadecanoic acid (5-MFHA) was proposed as a new myocardial imaging tracer for PET studies. From accumulation studies and metabolic studies of the heart muscle, 5-MFHA showed some properties, such as the relatively high initial uptake, the longer retention of myocardial accumulation and the quite similar metabolic pattern in the myocardium to that of straight-chain-fatty acids. These properties demonstrate that 5-MFHA is one of the structually modified fluorofatty acids and may be one of available myocardial imaging tracers. According to PET studies, this expectation is well supported.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "\u8457\u8005\u5225\u540d", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "103444", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Takahashi, Toshihiro"}]}]}, "item_7_publisher_7": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "\u65b0\u6f5f\u533b\u5b66\u4f1a"}]}, "item_7_select_19": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "\u9ad8\u6a4b, \u4fca\u535a"}], "nameIdentifiers": [{"nameIdentifier": "103443", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-07"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "113(1)_1-13.pdf", "filesize": [{"value": "1.9 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1900000.0, "url": {"label": "113(1)_1-13.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/16219/files/113(1)_1-13.pdf"}, "version_id": "d1b82a8c-d49f-4b38-9504-2f268f5b8ba2"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "[^\u003c11\u003eC]/[^\u003c18\u003eF]labeled fatty acid derivatives", "subitem_subject_scheme": "Other"}, {"subitem_subject": "PET", "subitem_subject_scheme": "Other"}, {"subitem_subject": "[^\u003c11\u003eC]HCN", "subitem_subject_scheme": "Other"}, {"subitem_subject": "5-methyl-17-[^\u003c18\u003eF]fluoroheptadecanoic acid", "subitem_subject_scheme": "Other"}, {"subitem_subject": "myocardial imaging tracers", "subitem_subject_scheme": "Other"}, {"subitem_subject": "[^\u003c11\u003eC]/[^\u003c18\u003eF]\u6a19\u8b58\u8102\u80aa\u9178\u8a98\u5c0e\u4f53", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u967d\u96fb\u5b50\u65ad\u5c64\u64ae\u50cf\u6cd5", "subitem_subject_scheme": "Other"}, {"subitem_subject": "[^\u003c11\u003eC]\u6a19\u8b58\u30b7\u30a2\u30f3\u5316\u6c34\u7d20", "subitem_subject_scheme": "Other"}, {"subitem_subject": "5-\u30e1\u30c1\u30eb-17-[^\u003c18\u003eF]\u30d5\u30eb\u30aa\u30ed\u30d8\u30d7\u30bf\u30c7\u30ab\u30f3\u9178", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u5fc3\u7b4b\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5264", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "\u967d\u96fb\u5b50\u653e\u51fa\u6838\u7a2e\u3067\u6a19\u8b58\u3055\u308c\u305f\u8102\u80aa\u9178\u95a2\u9023\u8a3a\u65ad\u85ac\u306e\u958b\u767a\u3068\u305d\u306e\u533b\u5b66\u5229\u7528", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "\u967d\u96fb\u5b50\u653e\u51fa\u6838\u7a2e\u3067\u6a19\u8b58\u3055\u308c\u305f\u8102\u80aa\u9178\u95a2\u9023\u8a3a\u65ad\u85ac\u306e\u958b\u767a\u3068\u305d\u306e\u533b\u5b66\u5229\u7528"}, {"subitem_title": "\u967d\u96fb\u5b50\u653e\u51fa\u6838\u7a2e\u3067\u6a19\u8b58\u3055\u308c\u305f\u8102\u80aa\u9178\u95a2\u9023\u8a3a\u65ad\u85ac\u306e\u958b\u767a\u3068\u305d\u306e\u533b\u5b66\u5229\u7528", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["453/456", "471/537/538/1100"], "permalink_uri": "http://hdl.handle.net/10191/46471", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2017-02-16"}, "publish_date": "2017-02-16", "publish_status": "0", "recid": "16219", "relation": {}, "relation_version_is_last": true, "title": ["\u967d\u96fb\u5b50\u653e\u51fa\u6838\u7a2e\u3067\u6a19\u8b58\u3055\u308c\u305f\u8102\u80aa\u9178\u95a2\u9023\u8a3a\u65ad\u85ac\u306e\u958b\u767a\u3068\u305d\u306e\u533b\u5b66\u5229\u7528"], "weko_shared_id": null}