{"created":"2021-03-01T06:20:45.666167+00:00","id":16188,"links":{},"metadata":{"_buckets":{"deposit":"2536e3a6-f04a-4e3b-a2bf-09701578f9d3"},"_deposit":{"id":"16188","owners":[],"pid":{"revision_id":0,"type":"depid","value":"16188"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00016188","sets":["453:456","471:537:538:1099"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Gene Expression and Function of Neuropeptide Y in the Sympathetic Neurons and Central Nervous System－Gene Regulation Involved in Neural Differentiation and Memory."}]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1999-02","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"82","bibliographicPageStart":"77","bibliographicVolumeNumber":"113","bibliographic_titles":[{"bibliographic_title":"新潟医学会雑誌"},{"bibliographic_title":"新潟医学会雑誌","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"It is an unsolved question how the neuron－specific genes are . regulated in the mature neurons. The neuronal regulation of neuropeptide Y （NPY） gene which is a cotransmitter of sympathetic neurons and expressed abundantly in the central nervous system. The regulation of this gene resembles that of tyrosine hydroxylase gene.Both the membrane depolarization induced by neural activity and neurotrophic factors such as NGF induced the transcriptiional activation of NPY and enkephalin genes. These mechanisms are due to both Ca/almodulin and MAPK （mitogen－activated protein kinase） dependent processes, respectively. These findings indicated that the transcriptional activations of neural genes are due to the novel transactivational mechanisms. The novel transcriptional factors will be reported.","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"103285","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Higuchi, Hiroshi"}]}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟医学会"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00182415","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00290440","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"樋口, 宗史"}],"nameIdentifiers":[{"nameIdentifier":"103284","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-07"}],"displaytype":"detail","filename":"113(2)_77-82.pdf","filesize":[{"value":"1.0 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"113(2)_77-82.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/16188/files/113(2)_77-82.pdf"},"version_id":"0438b767-2a2a-4b06-919b-5b9535389af7"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Gene expression","subitem_subject_scheme":"Other"},{"subitem_subject":"transcription","subitem_subject_scheme":"Other"},{"subitem_subject":"transcriptional factor","subitem_subject_scheme":"Other"},{"subitem_subject":"Neuropeptide Y","subitem_subject_scheme":"Other"},{"subitem_subject":"enkephalin A","subitem_subject_scheme":"Other"},{"subitem_subject":"cDNA cloning","subitem_subject_scheme":"Other"},{"subitem_subject":"neural differentiation","subitem_subject_scheme":"Other"},{"subitem_subject":"NGF","subitem_subject_scheme":"Other"},{"subitem_subject":"sympathetic neuron","subitem_subject_scheme":"Other"},{"subitem_subject":"synaptic plasticity","subitem_subject_scheme":"Other"},{"subitem_subject":"memory","subitem_subject_scheme":"Other"},{"subitem_subject":"depolarization","subitem_subject_scheme":"Other"},{"subitem_subject":"calmodulin","subitem_subject_scheme":"Other"},{"subitem_subject":"遺伝子発現","subitem_subject_scheme":"Other"},{"subitem_subject":"転写","subitem_subject_scheme":"Other"},{"subitem_subject":"転写因子","subitem_subject_scheme":"Other"},{"subitem_subject":"神経ペプチドY","subitem_subject_scheme":"Other"},{"subitem_subject":"エンケファリンA","subitem_subject_scheme":"Other"},{"subitem_subject":"cDNAクローニング","subitem_subject_scheme":"Other"},{"subitem_subject":"神経分化","subitem_subject_scheme":"Other"},{"subitem_subject":"神経成長因子","subitem_subject_scheme":"Other"},{"subitem_subject":"交感神経","subitem_subject_scheme":"Other"},{"subitem_subject":"シナプス可塑性","subitem_subject_scheme":"Other"},{"subitem_subject":"記憶","subitem_subject_scheme":"Other"},{"subitem_subject":"脱分極","subitem_subject_scheme":"Other"},{"subitem_subject":"カルモジュリン","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"交感神経・中枢神経の神経ペプチドNPYの遺伝子発現と機能 : 神経分化, 記憶に関わる遺伝子制御","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"交感神経・中枢神経の神経ペプチドNPYの遺伝子発現と機能 : 神経分化, 記憶に関わる遺伝子制御"},{"subitem_title":"交感神経・中枢神経の神経ペプチドNPYの遺伝子発現と機能 : 神経分化, 記憶に関わる遺伝子制御","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","1099"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-02-17"},"publish_date":"2017-02-17","publish_status":"0","recid":"16188","relation_version_is_last":true,"title":["交感神経・中枢神経の神経ペプチドNPYの遺伝子発現と機能 : 神経分化, 記憶に関わる遺伝子制御"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:47:46.805404+00:00"}