@article{oai:niigata-u.repo.nii.ac.jp:00001614, author = {Hoshino, Tsutomu and Kouda, Masanori and Abe, Takamasa and Sato, Tsutomu}, issue = {16}, journal = {Chemical communications, Chemical communications}, month = {Jul}, note = {Incubation of squalene with the site-directed mutant F605A of squalene–hopene cyclase from Alicyclobacillus acidocaldarius yielded many triterpenes consisting of the 6/6/5-fused tri-, 6/6/6/5-fused tetra-, and 6/6/6/6/5-fused pentacyclic skeletons, the function of F605 being assignable for facilitating the ring expansion and for stabilizing the hopanyl C22-cation, possibly via cation-π interactions.}, pages = {1485--1486}, title = {Functional analysis of Phe605, a conserved aromatic amino acid in squalene–hopene cyclases}, volume = {2000}, year = {2000} }