ログイン
言語:

WEKO3

  • トップ
  • ランキング
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

{"_buckets": {"deposit": "f645b3df-d0b5-49f5-b7f6-91dd6520757f"}, "_deposit": {"id": "1604", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "1604"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00001604", "sets": ["454", "484"]}, "item_5_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2004-02", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "84", "bibliographicPageStart": "79", "bibliographicVolumeNumber": "13", "bibliographic_titles": [{"bibliographic_title": "Cardiovascular Pathology"}, {"bibliographic_title": "Cardiovascular Pathology", "bibliographic_titleLang": "en"}]}]}, "item_5_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Our previous study revealed that the coxsackievirus and adenovirus receptor (CAR) is a homophilic cell adhesion molecule and may function as a sensor of cell-cell interactions in the brain and damaged heart. In this study, we investigated if CAR expression is involved in the formation of neointimal hyperplasia using a balloon injury model of rat carotid artery. Cultured vascular smooth muscle cells (SMCs) from rat aorta were also studied. CAR antigen was constitutively detected in the endothelial cells (ECs) but not in SMCs before injury. On day 5 after balloon injury, CAR was expressed strongly in the first layer of medial SMCs. Neointimal hyperplasia was observed on day 7, and strong expressions of CAR concomitantly with proliferating cell nuclear antigen (PCNA) were obvious in the neointimal SMCs, while CAR in medial SMCs disappeared. The expression of CAR mRNA reached a peak on day 7 and declined gradually to the basal levels. When the ECs regenerated on day 14, CAR antigen was observed in the ECs but disappeared in the neointima. CAR together with PCNA was expressed abundantly in the proliferating SMCs in vitro, and diminished in cells grown to a con fluent state. The abundant expression of CAR in the neointima may facilitate an adenoviral gene therapy.", "subitem_description_type": "Abstract"}]}, "item_5_full_name_3": {"attribute_name": "著者別名", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "4555", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "鳥羽, 健"}]}]}, "item_5_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Elsevier"}]}, "item_5_relation_14": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "info:doi/10.1016/S1054-8807(03)00137-6", "subitem_relation_type_select": "DOI"}}]}, "item_5_rights_15": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "Elsevier Inc."}]}, "item_5_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_5_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA10993310", "subitem_source_identifier_type": "NCID"}]}, "item_5_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "10548807", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Nasuno, Akimitsu"}], "nameIdentifiers": [{"nameIdentifier": "4543", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Toba, Ken"}], "nameIdentifiers": [{"nameIdentifier": "4544", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ozawa, Takuya"}], "nameIdentifiers": [{"nameIdentifier": "4545", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hanawa, Haruo"}], "nameIdentifiers": [{"nameIdentifier": "4546", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Osman, Yasser"}], "nameIdentifiers": [{"nameIdentifier": "4547", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hotta, Yuko"}], "nameIdentifiers": [{"nameIdentifier": "4548", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yoshida, Kaori"}], "nameIdentifiers": [{"nameIdentifier": "4549", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Saigawa, Takashi"}], "nameIdentifiers": [{"nameIdentifier": "4550", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kato, Kiminori"}], "nameIdentifiers": [{"nameIdentifier": "4551", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kuwano, Ryozo"}], "nameIdentifiers": [{"nameIdentifier": "4552", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Watanabe, Kenichi"}], "nameIdentifiers": [{"nameIdentifier": "4553", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Aizawa, Yoshifusa"}], "nameIdentifiers": [{"nameIdentifier": "4554", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-07-29"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "24_0010.pdf", "filesize": [{"value": "1.4 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1400000.0, "url": {"label": "24_0010.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/1604/files/24_0010.pdf"}, "version_id": "7cef95f9-cbcf-4ecc-9615-3a0f73612ee5"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Coxsackievirus and Adenovirus receptor (CAR)", "subitem_subject_scheme": "Other"}, {"subitem_subject": "intimal hyperplasia", "subitem_subject_scheme": "Other"}, {"subitem_subject": "vascular smooth muscle cells", "subitem_subject_scheme": "Other"}, {"subitem_subject": "balloon injury", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Expression of coxsackievirus and adenovirus receptor(CAR) in neointima of the rat carotid artery", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Expression of coxsackievirus and adenovirus receptor(CAR) in neointima of the rat carotid artery"}, {"subitem_title": "Expression of coxsackievirus and adenovirus receptor(CAR) in neointima of the rat carotid artery", "subitem_title_language": "en"}]}, "item_type_id": "5", "owner": "1", "path": ["454", "484"], "permalink_uri": "http://hdl.handle.net/10191/1185", "pubdate": {"attribute_name": "公開日", "attribute_value": "2007-04-23"}, "publish_date": "2007-04-23", "publish_status": "0", "recid": "1604", "relation": {}, "relation_version_is_last": true, "title": ["Expression of coxsackievirus and adenovirus receptor(CAR) in neointima of the rat carotid artery"], "weko_shared_id": null}
  1. 0 資料タイプ別
  2. 01 学術雑誌論文
  1. 300 医歯学総合病院
  2. 10 学術雑誌論文
  3. 10 査読済論文

Expression of coxsackievirus and adenovirus receptor(CAR) in neointima of the rat carotid artery

http://hdl.handle.net/10191/1185
http://hdl.handle.net/10191/1185
3eed3d7c-8c9c-4ade-ae48-8d3c06aa53ff
名前 / ファイル ライセンス アクション
24_0010.pdf 24_0010.pdf (1.4 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2007-04-23
タイトル
タイトル Expression of coxsackievirus and adenovirus receptor(CAR) in neointima of the rat carotid artery
タイトル
言語 en
タイトル Expression of coxsackievirus and adenovirus receptor(CAR) in neointima of the rat carotid artery
言語
言語 eng
キーワード
主題Scheme Other
主題 Coxsackievirus and Adenovirus receptor (CAR)
キーワード
主題Scheme Other
主題 intimal hyperplasia
キーワード
主題Scheme Other
主題 vascular smooth muscle cells
キーワード
主題Scheme Other
主題 balloon injury
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
著者 Nasuno, Akimitsu

× Nasuno, Akimitsu

WEKO 4543

Nasuno, Akimitsu

Search repository
Toba, Ken

× Toba, Ken

WEKO 4544

Toba, Ken

Search repository
Ozawa, Takuya

× Ozawa, Takuya

WEKO 4545

Ozawa, Takuya

Search repository
Hanawa, Haruo

× Hanawa, Haruo

WEKO 4546

Hanawa, Haruo

Search repository
Osman, Yasser

× Osman, Yasser

WEKO 4547

Osman, Yasser

Search repository
Hotta, Yuko

× Hotta, Yuko

WEKO 4548

Hotta, Yuko

Search repository
Yoshida, Kaori

× Yoshida, Kaori

WEKO 4549

Yoshida, Kaori

Search repository
Saigawa, Takashi

× Saigawa, Takashi

WEKO 4550

Saigawa, Takashi

Search repository
Kato, Kiminori

× Kato, Kiminori

WEKO 4551

Kato, Kiminori

Search repository
Kuwano, Ryozo

× Kuwano, Ryozo

WEKO 4552

Kuwano, Ryozo

Search repository
Watanabe, Kenichi

× Watanabe, Kenichi

WEKO 4553

Watanabe, Kenichi

Search repository
Aizawa, Yoshifusa

× Aizawa, Yoshifusa

WEKO 4554

Aizawa, Yoshifusa

Search repository
著者別名
識別子 4555
識別子Scheme WEKO
姓名 鳥羽, 健
抄録
内容記述タイプ Abstract
内容記述 Our previous study revealed that the coxsackievirus and adenovirus receptor (CAR) is a homophilic cell adhesion molecule and may function as a sensor of cell-cell interactions in the brain and damaged heart. In this study, we investigated if CAR expression is involved in the formation of neointimal hyperplasia using a balloon injury model of rat carotid artery. Cultured vascular smooth muscle cells (SMCs) from rat aorta were also studied. CAR antigen was constitutively detected in the endothelial cells (ECs) but not in SMCs before injury. On day 5 after balloon injury, CAR was expressed strongly in the first layer of medial SMCs. Neointimal hyperplasia was observed on day 7, and strong expressions of CAR concomitantly with proliferating cell nuclear antigen (PCNA) were obvious in the neointimal SMCs, while CAR in medial SMCs disappeared. The expression of CAR mRNA reached a peak on day 7 and declined gradually to the basal levels. When the ECs regenerated on day 14, CAR antigen was observed in the ECs but disappeared in the neointima. CAR together with PCNA was expressed abundantly in the proliferating SMCs in vitro, and diminished in cells grown to a con fluent state. The abundant expression of CAR in the neointima may facilitate an adenoviral gene therapy.
書誌情報 Cardiovascular Pathology
en : Cardiovascular Pathology

巻 13, 号 2, p. 79-84, 発行日 2004-02
出版者
出版者 Elsevier
ISSN
収録物識別子タイプ ISSN
収録物識別子 10548807
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA10993310
DOI
識別子タイプ DOI
関連識別子 info:doi/10.1016/S1054-8807(03)00137-6
権利
権利情報 Elsevier Inc.
著者版フラグ
値 author
戻る
0
views
See details
Views

Versions

Ver.1 2021-03-01 20:56:55.637742
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Cite as

エクスポート

OAI-PMH
  • OAI-PMH JPCOAR
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by WEKO3


Powered by WEKO3