@article{oai:niigata-u.repo.nii.ac.jp:00015406, author = {成田, 一衛}, issue = {6}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Jun}, note = {The data from large clinical trials are essential for practicing evidence based medicine (EBM). The main reasons why physicians and patients today are convinced of the merits of lowering elevated BPs come directly from the results of randomized, blinded, prospective, multicenter, large clinical trials that have conclusively proved that active treatment with medications reduces cardiovascular risk. The purpose of this chapter is to summarize the history of major clinical trials for the treatment of hypertensive patients.}, pages = {227--233}, title = {6)大規模試験からみた高血圧治療(シンポジウム 高血圧治療の進歩, 第556回新潟医学会)}, volume = {114}, year = {2000} }