@article{oai:niigata-u.repo.nii.ac.jp:00015031, author = {古寺, 邦夫 and 福永, 博 and 奥村, 弘史 and 森山, 裕之 and 熊野, 英典 and 岡部, 正明}, issue = {2}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Feb}, note = {Two cases of variant angina were observed in siblings. The 52-year-old younger sister suffered from intractable rest angina with marked elevation of the ST-segment in the inferior leads. Although her coronary arteriogram was normal, she suddenly died five months later. The 62-year-old elder brother also suffered from longstanding rest angina. Severe coronary spasm in the three vessels was provoked by acetylcholine during coronary arteriography which showed no significant organic stenosis. Recently, some investigators report that genetic factors may play a role in the etiology of vasospastic angina in some patients. Further examination of the genes related to coronary spasm is required to elucidate the mechanism of the spasm.}, pages = {43--53}, title = {同胞にみられた異型狭心症の2例}, volume = {115}, year = {2001} }