@article{oai:niigata-u.repo.nii.ac.jp:00014895, author = {田川, 実}, issue = {5}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {May}, note = {Some atrial fibrillation (Af) originates from the atrial myocardium extending into the pulmonary veins (PV). Since electrophysiologic characteristics of the atrial myocardium in the PV have not well been studied, we mapped the area of atrial activity in the PV and compared the inducibility of Af and ERP at three sites: left-sided superior and inferior PVs (SPV and LPV) and high right strium (RA), in 7 canine hearts. Methods: SPV and LPV werecatheters, bipolar electrograms were consecutively recorded from each PV to LA. Another catheter was placed at RA. Programmed electrical stimulation, which consisted of single and double extrastimulus (SE and DE) and burst pacing, was attempted from each anatomical site. Results: (1) In both SPV and LPV, atrial activity was recorded 4-5 cm from the atrio-pulmonary junction. (2) Conduction of atrial activity was heterogeneous in the PV. (3) ERP at PV measured at the basic drive of 300 ms (110 ± 15 ms in UPV and 101 ± 24 ms in LPV) was shorter than that of RA (139 ± 15 ms). (4) In all 7 hearts, Af was induced by programmed stimulation from UPV or LPV (SE in 4 hearts, DE in 2 hearts, burst pacing in 1 heart). On the other hand, Af was induced from RA in only one heart. Conclusions: Atrial electrograms were extensively recorded in the PV. Single atrial firing in the PV can initiate Af and this may be associated with shorter ERP in the area.}, pages = {183--192}, title = {心房細動の発症基盤としての肺静脈内心房筋の電気生理学的特徴}, volume = {115}, year = {2001} }