@article{oai:niigata-u.repo.nii.ac.jp:00014506, author = {塩入, 俊樹 and 細木, 俊宏 and 小嶋, 麻紀 and 染矢, 俊幸 and 板東, 武彦}, issue = {12}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Dec}, note = {In 1980 panic disorder (PD) appeared in the Diagnostic and Statistical Manual of Mental Disorders, 3rd edition(DSM-III)as an anxiety disorder. Patients with PD experience panic attacks characterized by episodes of intense anxiety, shortness of breath, tightness of chest, heart pounding, sweating, dizziness, tremulousness, and other autonomic symptoms. Both sympathetic and parasympathetic system dysfunctions have been implicated in the pathophysiology of panic attack. In the present study, we measured papillary light and cardiovascular reflexes to examine autonomic nervous function in 8 PD patients and 8 age and sex-matched normal control subjects. To our knowledge, using these new methods to evaluate autonomic nervous functions is a first trial in PD. These measurements were done before and after audiovisual stimulation, which was looking at video-images with vivid sound effects on a tangent screen with the distance of 2 m in the dark room(10 lux)for 15 min. In PD patients group, anxious severity (Sheehan’s Anxiety Scale) was relevant to the delay of cardiovascular reflex and the increased variability of papillary diameter by the audiovisual stimulation. Although this study is preliminary, these results suggest the dysfunction of autonomic nervous function in PD and the new available methods for autonomic nervous function.}, pages = {627--631}, title = {パニック障害の自律神経機能}, volume = {115}, year = {2001} }