@article{oai:niigata-u.repo.nii.ac.jp:00014223,
 author = {陳, 煒},
 issue = {8},
 journal = {新潟医学会雑誌, 新潟医学会雑誌},
 month = {Aug},
 note = {Nerve regeneration through end-to-side coaptation has been confirmed. The regenerating fibers are believed to sprout from the internodal space of the recipient nerve. A new nerve tracing technique allows this belief to be tested. By introducing a recombinant adenovirus vector containing the LacZ gene into a severed nerve, the regenerating nerve fiber can be traced to its origin. We used this tracing technique for the tracing of the regenerating nerve fiber after end-to-side nerve coaptation. The severed musculocutaneous nerve was coapted end-to-side to the median or ulnar nerve. In the median nerve recipient group, most of the regenerating fibers were coming down from proximal site and directly entered into the coapted musculocutaneous nerve. In the ulnar nerve recipient group, T-shaped sprouting fibers from the recipient nerve fibers were present suggesting internodal sprouting if there was no demonstrable pathway from the C 7 brachial plexus root to the ulnar nerve. Mixture patterns of the regenerating fibers going directly into the coapted musculocutaneous nerve segment and T-shaped sprouting fibers from the recipient nerve fibers were present if there was a communicating branch between the C 7 root and the ulnar nerve. This finding suggests that neurotropism for the reinnervation by the original neurons of the donor nerve may be more involved in end-to-side nerve repair than internodal sprouting from the recipient nerve.},
 pages = {369--384},
 title = {末梢神経端側吻合後における LacZ 遺伝子組み替えアデノウィルスを用いた神経再生経路の検討 ： ラット腕神経叢モデル},
 volume = {116},
 year = {2002}
}