@article{oai:niigata-u.repo.nii.ac.jp:00012633, author = {布施, 一郎}, issue = {3}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Mar}, note = {Anticoagulation by 5~10 days of heparin followed by warfarin is the foundation of therapy for acute pulmonary embolism (PE). Heparin should be guided by monitoring activated partial throm-boplastin time (aPTT), with a prolongation of 1.5~2.0 times the upper limit of normal being appropriate. When warfarin is replaced by heparin, it should be started on the last five days of heparin treatment, since five days are required to appear an anti-thrombotic effect of warfarin. Warfarin should be used at least 6 months and the optimal INK range is 2.5~3.0. Thrombolysis by urokinase is considered when encountered with patients, who show acute life-threatening PE such as cardiac arrest or cardiogenic shock.}, pages = {170--175}, title = {6 急性肺血栓塞栓症の治療の進歩(シンポジウム 最近の急性肺(血栓)塞栓症,第602回新潟医学会)}, volume = {119}, year = {2005} }